Evidence map›Paper›PMID 39702138›Full record

ArticleBMC ophthalmology2024

Spatial and morphologic features of lenses with different axial lengths in cataract patients: a swept-source optical coherence tomography-based study.

Chao Chen, Jiaqi Meng, Kaiwen Cheng, Ching Kang, Liguang Zhou, Haike Guo, Xiangjia Zhu

Abstract read
In one paragraph

Article in BMC ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Chao Chen *Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China.
Jiaqi Meng *Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China.
Kaiwen Cheng *Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China.
Ching KangEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China.
Liguang Zhou *Department of Ophthalmology, Fenghua Hospital of Traditional Chinese Medicine, Ningbo, 315500, Zhejiang, China. zhouliguang1982@163.com.
Haike Guo *Department of Ophthalmology, Shanghai Heping Eye Hospital, Shanghai, 200437, China. guohaike@hotmail.com.
Xiangjia Zhu *Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China. zhuxiangjia1982@126.com.

Funding

Clinical Research Plan of Shanghai Shenkang Hospital Development Center SHDC12020111National Natural Science Foundation of China 82122017, 82271069, 81870642, 82371040, 81970780, 81470613 and 81670835Science and Technology Innovation Action Plan of Shanghai Science and Technology Commission 23Y11909800 and 21S31904900Shanghai Municipal Key Clinical Specialty Program shslczdzk01901
6 · The paper itself

Abstract

backgroundTo investigate the spatial and morphologic features of lenses with different axial length (ALs) in cataract patients using swept-source optical coherence tomography (SS-OCT).

methodsTotally 105 eyes of 105 patients scheduled to have cataract surgery were included. Eyes were divided into the control (AL < 24.5 mm), moderate myopia (MM, 24.5 ≤ AL < 26 mm) and high myopia (HM, AL ≥ 26 mm) groups. Spatial features including lens vault (LV) and iris-to-lens distance (ILD), and morphologic features including radii of curvature of anterior and posterior surface (Ra, Rp), lens diameter (LD) and lens thickness (LT) were measured in eight directions by SS-OCT.

resultsSpatially, the HM group had larger LV and ILD than the control group (both P < .05). LV and ILD were negatively correlated with AL, respectively (LV: r = -.484, P < .0001; ILD: r = -.656, P < .0001). Morphologically, both MM and HM groups had greater Ra and Rp than the control group. Ra was positively correlated with AL (r = .622, P < .0001), while the relationship between Rp and AL was non-linear. Moreover, the MM and HM groups had larger LD than the control group (both P < .001). Anterior LT was thinner in the HM than in the MM group (P = .026), while posterior LT between these two groups was similar. When compared in eight directions, similar trends were seen in Ra, Rp and LD, and the HM group showed a greater difference in Ra between horizontal and vertical directions.

conclusionsThis SS-OCT-based study showed that longer axial length is associated with a flatter lens, which was mainly attributed to the increase of Ra and LD. Longitudinal studies would be necessary to establish a causal relationship and temporal progression.

Indexed as

Axial Length, EyeCataractLens, CrystallineTomography, Optical CoherenceAgedAged, 80 and overCataract ExtractionFemaleHumansMaleMiddle AgedMyopiaRetrospective StudiesVisual AcuityAxial lengthCataractLens morphologyLens positionSS-OCT

Identifiers

PMID39702138
PMCPMC11660780

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.