Evidence map›Paper›PMID 39702015›Full record

ArticleSubstance use & misuse2025

Alex Rains, Erin Augustine, Kyle Miller, John Bresett, Rebecca Bolinski, Trevor Thompson, Babatunde Patrick Ajayi, Will Nicholson, Scott Fletcher, Wiley D Jenkins and 3 more

Abstract read
In one paragraph

Article in Substance use & misuse, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Alex RainsDepartment of Medicine, University of Chicago, Chicago, Illinois, USA.ORCID 0009-0002-7207-0780
Erin AugustineDepartment of Medicine, University of Chicago, Chicago, Illinois, USA.
Kyle MillerDepartment of Population Science and Policy, Southern Illinois University, Carbondale, Illinois, USA.
John BresettDepartment of Population Science and Policy, Southern Illinois University, Carbondale, Illinois, USA.
Rebecca BolinskiDepartment of Population Science and Policy, Southern Illinois University, Carbondale, Illinois, USA.
Trevor ThompsonDepartment of Population Science and Policy, Southern Illinois University, Carbondale, Illinois, USA.
Babatunde Patrick AjayiCommunity Health Sciences, School of Public Health, University of California Berkeley, Berkeley, California, USA.
Will NicholsonThe Community Action Place, Carbondale, Illinois, USA.
Scott FletcherThe Community Action Place, Carbondale, Illinois, USA.
Wiley D JenkinsDepartment of Epidemiology and Biostatistics, SIU School of Medicine, Springfield, Illinois, USA.
Mai T PhoDepartment of Medicine, University of Chicago, Chicago, Illinois, USA.
Lawrence J OuelletDivision of Epidemiology and Biostatistics, School of Public Health, University of Illinois Chicago, Chicago, Illinois, USA.
Jerel M EzellCommunity Health Sciences, School of Public Health, University of California Berkeley, Berkeley, California, USA.

Funding

Ending transmission of HIV, HCV, and STDs and overdose in rural communities of people who inject drugs (ETHIC)UH3DA044829 · NIDA · UNIVERSITY OF CHICAGO · PI JENKINS, WILEY, PHO, MAI TUYET · 2019 to 2022
$5.2M
NIDA NIH HHS UH3 DA044829
6 · The paper itself

Abstract

backgroundMethamphetamine use is disproportionately high in rural settings, with rates increasing during the COVID-19 pandemic. While syringe service programs reduce disease transmission among people who inject drugs, limited research exists around the value of smoking equipment, specifically pipes, in minimizing harms associated with rural methamphetamine use.

methodsWe conducted semi-structured interviews with people who use methamphetamine in rural southern Illinois. Inclusion criteria involved methamphetamine use in the past 30 days. Interview guides explored attitudes and behaviors regarding pipe use practices and pipe access. Interviews were recorded, transcribed, and coded. The data were analyzed for emergent themes using a sequential, deductive process.

resultsNineteen participants, average age 37.1 (SD + 8.7), were interviewed. 53% were women, and 89% were white. All reported smoking methamphetamine, and 84% reported injecting. Participants reported engaging in smoking instead of injection to decrease wounds, pain, and infections. Smoking enabled some to use socially as opposed to alone, as was typically the case when they injected. Participants expressed interest in pipe distribution through a harm reduction agency. They shared that, were a harm reduction agency to distribute pipes, it would connect people to other services such as HIV testing, naloxone, and safer sex supplies.

conclusionsPipe distribution may function as a harm reduction strategy by decreasing injection and solitary drug use and linking patients to additional services. Given disproportionate methamphetamine use in rural regions, this intervention could specifically address drug-related harms that impact rural populations.

Indexed as

Amphetamine-Related DisordersHarm ReductionMethamphetamineSubstance Abuse, IntravenousAdultCOVID-19FemaleHumansIllinoisMaleMiddle AgedRural PopulationMethamphetamineharm reductionmethmethamphetaminepipespipsRuralsmoking

Identifiers

PMID39702015
PMCPMC11825270

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.