Evidence map›Paper›PMID 39701567›Full record

SynthesisBiopsychosocial science and medicine2025

Sleep During Pregnancy and Offspring Outcomes From Infancy to Childhood: A Systematic Review.

Melissa Nevarez-Brewster, Deborah Han, Erin L Todd, Paige Keim, Jenalee R Doom, Elysia Poggi Davis

Abstract readSystematic Review
In one paragraph

Synthesis in Biopsychosocial science and medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Synergistic pathways to psychosis: understanding developmental risk and resilience factors.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Melissa Nevarez-BrewsterFrom the Department of Psychology (Nevarez-Brewster, Han, Todd, Keim, Doom, Davis), University of Denver, Denver, Colorado; and Department of Pediatrics (Davis), University of California, Irvine, California.ORCID 0000-0002-8198-8297
Deborah Han
Erin L Todd
Paige Keim
Jenalee R Doom
Elysia Poggi DavisORCID 0000-0001-6345-9271

Funding

Reducing Fetal Exposure to Maternal Depression to Improve Infant Risk MechanismsR01MH109662 · NIMH · UNIVERSITY OF DENVER (COLORADO SEMINARY) · PI DAVIS, ELYSIA POGGI, HANKIN, BENJAMIN L · 2017 to 2021
$4.0M
Reducing maternal prenatal depression to improve child cardiovascular healthR01HL155744 · NHLBI · UNIVERSITY OF DENVER (COLORADO SEMINARY) · PI DAVIS, ELYSIA POGGI, DOOM, JENALEE RAE · 2021 to 2025
$3.6M
Testing cortisol dysregulation as a mediator between early stress and adolescent cardiovascular healthK01HL143159 · NHLBI · UNIVERSITY OF DENVER (COLORADO SEMINARY) · PI DOOM, JENALEE RAE · 2019 to 2023
$788k
NHLBI NIH HHS K01 HL143159NHLBI NIH HHS R01 HL155744NIMH NIH HHS R01 MH109662
6 · The paper itself

Abstract

objectivePrenatal sleep problems have been previously linked to poor birth outcomes. However, much less is known about the associations between poor prenatal maternal sleep and offspring outcomes after birth. The purpose of this systematic review was to synthesize the findings linking prenatal maternal sleep health and offspring health and development during infancy and childhood.

methodsA total of 4650 nonduplicate articles were identified via PsycInfo and PubMed databases. After screening and full-text review, 34 articles met the inclusion criteria and were extracted for information.

resultsThe bulk of studies in this review (n = 19; 76.5%) were published between 2019 and 2024. Measures of prenatal sleep included sleep timing, quality, sleep disorders and/or symptoms of disorders, and daytime sleepiness. Offspring outcomes were categorized as follows: a) sleep health (e.g., nighttime sleep duration, night wakings), b) physical health (e.g., body mass index, hospitalizations), c) child developmental outcomes (e.g., global development, negative affect, executive functioning), and d) brain structure and function (e.g., brain volume, event-related potentials). Evidence consistently links poor prenatal sleep health to poorer offspring sleep, higher body mass index, higher prevalence of physical health conditions, poorer global development, and more behavioral problems. Emerging evidence also links prenatal sleep to differences in offspring brain structure and function.

conclusionsPoor prenatal maternal sleep health may be an environmental signal that informs offspring health. Future studies are needed to fully understand the pervasive, intergenerational, and long-lasting effects of sleep across pregnancy.

Indexed as

Child DevelopmentPrenatal Exposure Delayed EffectsSleep Wake DisordersChildChild, PreschoolFemaleHumansInfantPregnancyPregnancy Complications

Identifiers

PMID39701567
PMCPMC12747718

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.