Evidence map›Paper›PMID 39701557›Full record

ArticleJournal of veterinary internal medicine

Leukoreduction in a dog with acute leukemia.

Brenna Hanratty, Anna Hauck, Amanda Foskett, J D Foster

Abstract readCase Reports
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Leukoreduction in a dog with acute leukemia.Journal of veterinary internal medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Brenna HanrattyFriendship Hospital for Animals, Washington, District of Columbia, USA.
Anna HauckFriendship Hospital for Animals, Washington, District of Columbia, USA.ORCID https://orcid.org/0009-0002-5846-5583
Amanda FoskettFriendship Hospital for Animals, Washington, District of Columbia, USA.
J D FosterFriendship Hospital for Animals, Washington, District of Columbia, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 9-year-old male castrated golden retriever cross was evaluated for an acute onset of ataxia. A complete blood count revealed marked leukocytosis, anemia, and thrombocytopenia. Leukocytosis was characterized by marked lymphocytosis, monocytosis, neutropenia, and eosinopenia. Flow cytometry identified CD34+ leukocytosis with cells that did not express lineage antigens, suggesting the most likely diagnosis of either acute lymphoid or myeloid leukemia. Leukoreduction via leukapheresis was elected to reduce the disease burden before initiating chemotherapy. Postleukoreduction, the dog had a 54% decrease in their white blood cell count. The dog completed multiple weeks of traditional cyclophosphamide, doxorubicin, vincristine, prednisone (CHOP)-based treatment and had a survival time of 43 days before the owner elected humane euthanasia. To our knowledge, this report represents a case of acute leukemia in a dog treated with leukoreduction before starting chemotherapy.

Indexed as

Dog DiseasesAnimalsAntineoplastic Combined Chemotherapy ProtocolsDogsLeukapheresisLeukemiaLeukemia, Myeloid, AcuteMalechemotherapyhyperleukocytosisleukapheresislymphoblastoncologyveterinary

Identifiers

PMID39701557
PMCPMC11658807

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.