Evidence map›Paper›PMID 39701157›Full record

ArticleThe Journal of parasitology2024

A RAPID DIAGNOSTIC PCR ASSAY FOR THE DETECTION OF SCHISTOSOMA MANSONI IN THEIR SNAIL VECTORS.

Tom Pennance, Yvonne Lam, Nathaniel Bigot, Joshua Trapp, Johannie M Spaan, George Ogara, Fredrick Rawago, Kennedy Andiego, Boaz Mulonga, Meredith Odhiambo and 4 more

Abstract read
In one paragraph

Article in The Journal of parasitology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Genetic Diversity and Infection Prevalence ofInternational journal of molecular sciences · 2025
    Article
  2. Article
  3. Article
  4. Mating system ofCurrent research in parasitology & vector-borne diseases · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yvonne Lam
Nathaniel Bigot
Joshua Trapp
Johannie M Spaan
George Ogara
Fredrick Rawago
Kennedy Andiego
Boaz Mulonga
Meredith Odhiambo
Martin W Mutuku
Eric S Loker
Maurice R Odiere
Michelle L Steinauer

Funding

Identifying schistosomiasis resistance genes of snail vectors in hotspot transmission zones: Translating from laboratory models to the field.R01AI141862 · NIAID · WESTERN UNIVERSITY OF HEALTH SCIENCES · PI STEINAUER, MICHELLE L. · 2019 to 2023
$1.7M
NIAID NIH HHS R01 AI141862
6 · The paper itself

Abstract

Accurate detection of schistosome infections in snails is vital for epidemiologic and laboratory studies. Traditional microscopy methods to detect schistosomes in snails are hindered by long prepatent periods and snail survivorship, leading to inaccurate assessment of infections. A rapid, multiplexed PCR assay targeting Biomphalaria sudanica or Biomphalaria glabrata (internal control) and Schistosoma mansoni DNA is described. The method takes less than 90 min starting from extracted snail DNA and is successful at amplifying schistosome DNA in snail tissue as soon as 30 min following exposure. Accurate measures of schistosome infection success in snails (compatibility) are possible by 4-7 days postexposure.

Indexed as

BiomphalariaDNA, HelminthSchistosoma mansoniAnimalsMultiplex Polymerase Chain ReactionPolymerase Chain ReactionRapid Diagnostic TestsSchistosomiasis mansoniDNA, HelminthBiomphalaria glabrataBiomphalaria sudanicaCompatibilityDiagnosticsSchistosoma mansoniSnailSusceptibilityVectorXenomonitoring

Identifiers

PMID39701157
PMCPMC12175291

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.