Evidence map›Paper›PMID 39701113›Full record

ArticleThe Lancet. Public health2025

Improving implementation of needle and syringe programmes to expand, scale up, and sustain evidence-based prevention interventions for HIV and hepatitis C in prisons.

Nadine Kronfli, Daniel J Bromberg, Hans Wolff, Linda Montanari, Serheii Vasyliev, Frederick L Altice

Abstract read
In one paragraph

Article in The Lancet. Public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  7. Reimagining Hepatitis C Elimination: Time for Actions, Not Targets.Journal of the International AIDS Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nadine KronfliDepartment of Medicine, Division of Infectious Disease and Chronic Viral Illness Service, McGill University, Montreal, QC, Canada; Centre for Outcomes Research and Evaluation, Research Institute of the McGill University Health Centre, Montreal, QC, Canada. Electronic address: nadine.kronfli@mcgill.ca.
Daniel J BrombergDepartment of Social and Behavioral Sciences, Yale School of Public Health, Yale University, New Haven, CT, USA; Heidelberg Institute of Global Health, University of Heidelberg, Heidelberg, Germany; Department of Psychiatry and Psychotherapy (Campus Charité Mitte), Charité-Universitätsmedizin Berlin, Berlin, Germany.
Hans WolffDivision of Prison Health, Geneva University Hospitals & University of Geneva, Geneva, Switzerland.
Linda MontanariEuropean Union Drugs Agency, Lisbon, Portugal.
Serheii VasylievHealth Care Center of the State Criminal Executive Service of Ukraine, Kyiv, Ukraine.
Frederick L AlticeDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, Yale University, New Haven, CT, USA; Department of Medicine, Section of Infectious Diseases, Yale School of Medicine, Yale University, New Haven, CT, USA.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Prison Interventions and HIV Prevention CollaborationR01DA029910 · NIDA · YALE UNIVERSITY · PI FREDERICK LEWIS ALTICE · 2010 to 2026
$7.9M
Expanding Medication Assisted Therapy in Ukraine (ExMAT)R01DA033679 · NIDA · YALE UNIVERSITY · PI ALTICE, FREDERICK LEWIS · 2012 to 2021
$6.4M
Expanding Medication Assisted Therapies in Central AsiaR01DA054851 · NIDA · YALE UNIVERSITY · PI FREDERICK LEWIS ALTICE, Lynn Madden · 2022 to 2026
$2.9M
Malaysian Implementation Science Training (MIST) Program in HIVD43TW011324 · FIC · YALE UNIVERSITY · PI FREDERICK LEWIS ALTICE, Rafdzah Zaki · 2020 to 2026
$1.8M
Identifying Challenges and Opportunities for PrEP Uptake Among Women at Elevated HIV Risk in GeorgiaD43TW012492 · FIC · YALE UNIVERSITY · PI FREDERICK LEWIS ALTICE, Denise Esserman · 2023 to 2026
$1.3M
Modeling the impact and cost-effectiveness of opioid agonist treatments to reduce the negative consequences of incarceration on HIV and TB transmission in Eastern Europe and Central AsiaR21DA047902 · NIDA · YALE UNIVERSITY · PI ALTICE, FREDERICK LEWIS · 2020 to 2021
$378k
FIC NIH HHS D43 TW011324FIC NIH HHS D43 TW012492NCATS NIH HHS UL1 TR001863NIDA NIH HHS R01 DA029910NIDA NIH HHS R01 DA033679NIDA NIH HHS R01 DA054851NIDA NIH HHS R21 DA047902
6 · The paper itself

Abstract

The 1990 resolution by the UN General Assembly committed member states to provide health-care equity for people in prison, who are included in the global goals to control HIV and eliminate hepatitis C virus (HCV) by 2030. WHO has set ambitious HCV elimination targets by including people who inject drugs (PWID), yet has not prioritised PWID who are incarcerated, a substantial population who have or are at risk for HCV infection. Human rights principles of health-care equity stipulate that "prisoners should enjoy the same standards of health care that are available in the community, without discrimination on the grounds of their legal status". Globally, only nine countries provide prison-based needle and syringe programmes (PNSPs), essential evidence-based interventions to holistically reduce the harms from drug use, of which only three countries extend reach to all prisons. Even where available, these services are accessed by few participants. PNSPs are recommended as an essential element of an effective HIV and HCV prevention strategy in prisons, and studies have shown that they are key to achieving HCV elimination in carceral settings. This Viewpoint, based primarily on unpublished data from key country-level stakeholders and expert opinion, highlights our perspective that implementation factors related to PNSP delivery in diverse settings likely contribute to low adoption and use of these services by PWID in prisons compared with in the community. However, successful expansion of these evidence-based interventions will depend on political commitment, national surveillance and monitoring programmes, and state-of-the-art implementation science methods, where inputs from multilevel stakeholders should guide improved implementation. Policy makers are urged to create and support opportunities to scale up PNSPs within countries where they exist and expand them to other countries where they are needed to solidify years of commitment towards the 2030 HCV elimination goals.

Indexed as

Hepatitis CHIV InfectionsNeedle-Exchange ProgramsPrisonsEvidence-Based PracticeHumansPrisonersSubstance Abuse, Intravenous

Identifiers

PMID39701113
PMCPMC11823114

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.