ArticleCell2025
The auditory midbrain mediates tactile vibration sensing.
Article in Cell, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- A Molecularly Defined Midbrain Circuit Mechanism for Sound-Driven Defensive Behavior and Anxiety.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Targeting GCell reports. Medicine · 2026Article
- Molecular taxonomy and spatial organization define neuronal subtypes in the mouse inferior colliculus.iScience · 2026Article
- Article
- Rethinking hierarchy: the auditory system as an integrated cortical-subcortical network.Nature reviews. Neuroscience · 2026Review
- Ascending inputs to inferior colliculus subdivisions reveal pathway-specific hybrid organization in the external cortex.bioRxiv : the preprint server for biology · 2026Article
- Locomotion-induced neural activity independent of auditory feedback in the mouse inferior colliculus.iScience · 2026Article
- Velocity sensitivity of mechanotransduction in the afferent terminal underlies vibration detection in the Pacinian corpuscle.Nature communications · 2026Article
- A Tangentially Sensitive Tactile Sensor Reveals the Stick-Slip Mechanism and Enhances Robotic Tactile Sensing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Fast-conducting mechanonociceptors uniquely engage reflexive and affective pain circuitry to drive protective responses.bioRxiv : the preprint server for biology · 2025Article
- Multisensory Integration for Identifying the Milling States in Robot-Assisted Cervical Laminectomy.Orthopaedic surgery · 2025Article
- Lamellar Schwann cells in the Pacinian corpuscle potentiate vibration perception.Science advances · 2025Article
- Divergent neural circuits for proprioceptive and exteroceptive sensing of the Drosophila leg.Nature communications · 2025Article
- Emergent Aspects of the Integration of Sensory and Motor Functions.Brain sciences · 2025Review
- An Integrated Monolithic Synaptic Device for C-Tactile Afferent Perception and Robot Emotional Interaction.Cyborg and bionic systems (Washington, D.C.) · 2025Article
- Auditory pathway for detection of vibration in the tokay gecko.Current biology : CB · 2024Article
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12 authors.
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Abstract
Vibrations are ubiquitous in nature, shaping behavior across the animal kingdom. For mammals, mechanical vibrations acting on the body are detected by mechanoreceptors of the skin and deep tissues and processed by the somatosensory system, while sound waves traveling through air are captured by the cochlea and encoded in the auditory system. Here, we report that mechanical vibrations detected by the body's Pacinian corpuscle neurons, which are distinguished by their ability to entrain to high-frequency (40-1,000 Hz) environmental vibrations, are prominently encoded by neurons in the lateral cortex of the inferior colliculus (LCIC) of the midbrain. Remarkably, most LCIC neurons receive convergent Pacinian and auditory input and respond more strongly to coincident tactile-auditory stimulation than to either modality alone. Moreover, the LCIC is required for behavioral responses to high-frequency mechanical vibrations. Thus, environmental vibrations captured by Pacinian corpuscles are encoded in the auditory midbrain to mediate behavior.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.