Evidence map›Paper›PMID 39700912›Full record

ArticleDevelopmental cognitive neuroscience2025

How will developmental neuroimaging contribute to the prediction of neurodevelopmental or psychiatric disorders? Challenges and opportunities.

Koraly Pérez-Edgar, Mary Dozier, Rebecca Saxe, Katherine E MacDuffie

Abstract read
In one paragraph

Article in Developmental cognitive neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Koraly Pérez-EdgarDepartment of Psychology, Penn State University, USA.
Mary DozierDepartment of Psychological & Brain Sciences, University of Delaware, USA.
Rebecca SaxeDepartment of Brain and Cognitive Sciences, Massachusetts Institute of Technology, USA.
Katherine E MacDuffieTreuman Katz Center for Pediatric Bioethics and Palliative Care, Seattle Children's Research Institute, USA; Department of Pediatrics, University of Washington School of Medicine, USA. Electronic address: kate.macduffie@seattlechildrens.org.

Funding

Specialized services for high-risk birth parentsR01MH074374 · NIMH · UNIVERSITY OF DELAWARE · PI DOZIER, MARY, TOTTENHAM, NIM · 2006 to 2023
$10.1M
13/24 The Healthy Brain and Child Development National ConsortiumU01DA055361 · NIDA · PENNSYLVANIA STATE UNIVERSITY, THE · PI Koraly E Perez-Edgar, Aleksandra Ewa Zgierska · 2021 to 2026
$7.8M
Understanding the Interplay between Parent and Child Contributions in Parent-Child Anxiety TransmissionR01MH130007 · NIMH · PENNSYLVANIA STATE UNIVERSITY, THE · PI Koraly E Perez-Edgar, Susan B Perlman · 2022 to 2026
$5.8M
Intervening with Opioid-Dependent Mothers Living in Poverty: Effects on Mothers' and Infants' Behavioral and Biological RegulationR01HD098525 · NICHD · UNIVERSITY OF DELAWARE · PI DOZIER, MARY · 2020 to 2024
$3.1M
How do Cortical regions selective for visual scenes develop in human infants?R01HD103847 · NICHD · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI SAXE, REBECCA R · 2021 to 2025
$1.6M
The experience of human subjects with brain organoid researchR00MH125328 · NIMH · SEATTLE CHILDREN'S HOSPITAL · PI MACDUFFIE, KATE E. · 2022 to 2024
$711k
NICHD NIH HHS R01 HD098525NICHD NIH HHS R01 HD103847NIDA NIH HHS U01 DA055361NIMH NIH HHS R00 MH125328NIMH NIH HHS R01 MH074374NIMH NIH HHS R01 MH130007
6 · The paper itself

Abstract

Successful developmental neuroimaging efforts require interdisciplinary expertise to ground scientific questions in knowledge of human development, modify and create technologies and data processing pipelines suited to the young brain, and ensure research procedures meet the needs and protect the interests of young children and their caregivers. This paper brings together four interdisciplinary perspectives to tackle a set of questions that are central for the field to address as we imagine a future role for developmental neuroimaging in the prediction of neurodevelopmental or psychiatric disorders: 1) How do we generate a strong evidence base for causality and clinical relevance? 2) How do we ensure the integrity of the data and support fair and wide access? 3) How can these technologies be implemented in the clinic? 4) What are the ethical obligations for neuroimaging researchers working with infants and young children?

Indexed as

BrainMental DisordersNeurodevelopmental DisordersNeuroimagingChildHumansInfantBioethicsNeurodevelopmental disordersNeuroimagingPredictionPsychiatric disorders

Identifiers

PMID39700912
PMCPMC11721882

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.