Evidence map›Paper›PMID 39700515›Full record

ArticleAmerican journal of respiratory cell and molecular biology2025

LPS Increases Artery but Not Airway Contraction in Precision-Cut Lung Slices from a Mouse Model of Acute Respiratory Distress Syndrome.

Emma Lamanna, Zoe F Kropf, Raymond Luong, Matthew Narayan, Elizabeth A Richards, Bailey Cardwell, Simon G Royce, Claudia A Nold-Petry, Jane E Bourke

Abstract read
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In one paragraph

Article in American journal of respiratory cell and molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Emma LamannaBiomedicine Discovery Institute, Department of Pharmacology, Monash University, Clayton, Victoria, Australia.
Zoe F KropfBiomedicine Discovery Institute, Department of Pharmacology, Monash University, Clayton, Victoria, Australia.
Raymond LuongBiomedicine Discovery Institute, Department of Pharmacology, Monash University, Clayton, Victoria, Australia.
Matthew NarayanBiomedicine Discovery Institute, Department of Pharmacology, Monash University, Clayton, Victoria, Australia.
Elizabeth A RichardsBiomedicine Discovery Institute, Department of Pharmacology, Monash University, Clayton, Victoria, Australia.
Bailey CardwellBiomedicine Discovery Institute, Department of Pharmacology, Monash University, Clayton, Victoria, Australia.
Simon G RoyceBiomedicine Discovery Institute, Department of Pharmacology, Monash University, Clayton, Victoria, Australia.
Claudia A Nold-PetryRitchie Centre, Hudson Institute of Medical Research, Clayton, Victoria, Australia; and.
Jane E BourkeBiomedicine Discovery Institute, Department of Pharmacology, Monash University, Clayton, Victoria, Australia.ORCID 0000-0001-7314-9234

Funding

National Health and Medical Research Council APP1187755
6 · The paper itself

Abstract

Acute respiratory distress syndrome (ARDS) results in decreased quality of life, including increased risk of pulmonary hypertension (PH). In animal models, ARDS can be induced by LPS, which can disrupt the pulmonary endothelium and epithelium and induce inflammation. We tested whether

Indexed as

LipopolysaccharidesLungPulmonary ArteryRespiratory Distress SyndromeVasoconstriction15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic AcidAnimalsDisease Models, AnimalEndothelin-1MaleMiceMice, Inbred C57BLSerotoninTumor Necrosis Factor-alpha15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic AcidEndothelin-1LipopolysaccharidesSerotoninTumor Necrosis Factor-alphaacute respiratory distress syndromeLPSprecision-cut lung slicepulmonary hypertension

Identifiers

PMID39700515

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.