ArticleScience (New York, N.Y.)2025
Identification of antigen-presenting cell-T cell interactions driving immune responses to food.
Abstract read
In one paragraph
Article in Science (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed.
- Metabolic sensor AMPK licenses intestinal CD103Science advances · 2026Article
- Immune tolerance platforms to mitigate unwanted immune responses.Journal of pharmaceutical sciences · 2026Review
- T cell fate is dictated by different antigen-presenting cells in response to dietary versus gut epithelial self-antigen.Immunity · 2026Article
- Article
- Spatiotemporally Resolved Protein Tagging for Dynamic and Tissue-Specific Secretome Profiling In Vivo.Angewandte Chemie (International ed. in English) · 2026Article
- Therapeutic Potential of Polysaccharide-Modulated Gut Microbiota-Immune Axis in Gastrointestinal Cancers: Modern Insights From Traditional Pharmacy.Molecular nutrition & food research · 2026Review
- Harnessing mucosal immunity for protective vaccines.Nature reviews. Immunology · 2026Review
- The long noncoding RNA lnc13 restrains inflammatory responses to maintain oral tolerance to gluten.Nature immunology · 2026Article
- How crosstalk at the immune synapse shapes T cell and dendritic cell biology.Nature reviews. Immunology · 2026Review
- T cell fate regulation in EBV‑associated nasopharyngeal carcinoma (Review).Oncology reports · 2026Review
- The Gut-Pancreas Axis in Type 1 Diabetes: Emerging Insights into Microbiota and Immune Interactions.International journal of molecular sciences · 2026Review
- Article
- Mechanisms of IgE-mediated food allergy and the role of allergen-specific B cells.FEBS letters · 2026Review
- Intestinal Microfold Cells Play a Critical Role in the Uptake and Oral Tolerance Mediated by Lysophosphatidylserine-Containing Lipidic Nanoparticles.Nanomaterials (Basel, Switzerland) · 2026Article
- Bioengineering Interventions to Enhance the Capacity of the Gut Microbiota in Controlling Food Allergies.Life (Basel, Switzerland) · 2026Review
- The human immunome in the post-schistosomiasis mass drug administration era.PLoS neglected tropical diseases · 2026Review
- RORγtNature communications · 2026Article
- RORγtScience immunology · 2026Article
- Thymic myeloid cells are heterogenous and include a novel population of transitional dendritic cells.The Journal of experimental medicine · 2026Article
- Specialized Dendritic Cells Mediating Peripheral Tolerance to Intestinal Antigens.Immunological reviews · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Maria Cecilia Campos CanessoLaboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA.ORCID 0000-0002-2562-662X
Tiago Bruno Rezende de Castro *Laboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA.ORCID 0000-0002-0359-0611
Sandra Nakandakari-Higa *Laboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, USA.
Ainsley LockhartLaboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA.ORCID 0000-0003-0304-4618
Julia LuehrLaboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA.ORCID 0009-0000-8776-0579
Juliana BortolattoLaboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, USA.ORCID 0000-0001-8779-5464
Roham ParsaLaboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA.ORCID 0000-0002-0864-6098
Daria EsterházyDepartment of Pathology, University of Chicago, Chicago, IL, USA.
Mengze LyuJoan and Sanford I. Weill Department of Medicine, Division of Gastroenterology and Hepatology, Department of Microbiology and Immunology, Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.ORCID 0000-0002-8509-7969
Tian-Tian LiuDepartment of Pathology and Immunology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.
Kenneth M MurphyDepartment of Pathology and Immunology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-3505-9630
Gregory F SonnenbergJoan and Sanford I. Weill Department of Medicine, Division of Gastroenterology and Hepatology, Department of Microbiology and Immunology, Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.ORCID 0000-0003-0948-5908
Bernardo S ReisLaboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA.ORCID 0000-0002-6841-116X
Gabriel D VictoraLaboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, USA.ORCID 0000-0001-8807-348X
Daniel MucidaLaboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA.ORCID 0000-0002-0000-0452
Funding
Transgenic CoreP01AI179273 · NIAID · FOOD ALLERGY SCIENCE INITIATIVE, INC. · PI Daniel S Mucida · 2024 to 2026
$9.4MINTESTINAL REGULATION OF ThPOK EXPRESSION AND CD4 HELPER T CELL FUNCTIONR01DK093674 · NIDDK · ROCKEFELLER UNIVERSITY · PI Daniel S Mucida · 2013 to 2026
$7.0MQuantifying Cell-Cell Interactions in the Immune System by Trans-Synaptic LabelingDP1AI144248 · NIAID · ROCKEFELLER UNIVERSITY · PI VICTORA, GABRIEL D · 2018 to 2022
$5.9MIntestinal surveillance by intraepithelial lymphocytesR01DK113375 · NIDDK · ROCKEFELLER UNIVERSITY · PI Semir Beyaz, Daniel S Mucida · 2017 to 2026
$5.5MB cell clonal selection in gut-associated germinal centersR01AI157137 · NIAID · ROCKEFELLER UNIVERSITY · PI Daniel S Mucida, Gabriel D Victora · 2020 to 2026
$4.8MMolecular Basis of cDC1 DevelopmentR01AI162643 · NIAID · WASHINGTON UNIVERSITY · PI MURPHY, KENNETH M · 2022 to 2025
$2.8MFunction of Wdfy4 in cross-presentation and immunityR01AI150297 · NIAID · WASHINGTON UNIVERSITY · PI MURPHY, KENNETH M · 2019 to 2023
$2.5MCell-cell interactions driving gut inflammation and toleranceK99AI173537 · NIAID · ROCKEFELLER UNIVERSITY · PI CAMPOS CANESSO, MARIA CECILIA · 2023 to 2024
$279kDefining novel mechanisms of microbiota in regulating anti-tumor responsesK99CA290052 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI LYU, MENGZE · 2024 to 2025
$276kHoward Hughes Medical InstituteNCI NIH HHS K99 CA290052NIAID NIH HHS DP1 AI144248NIAID NIH HHS K99 AI173537NIAID NIH HHS P01 AI179273NIAID NIH HHS R01 AI150297NIAID NIH HHS R01 AI157137NIAID NIH HHS R01 AI162643NIDDK NIH HHS R01 DK093674NIDDK NIH HHS R01 DK113375Wellcome Trust
Abstract
The intestinal immune system must concomitantly tolerate food and commensals and protect against pathogens. Antigen-presenting cells (APCs) orchestrate these immune responses by presenting luminal antigens to CD4
Indexed as
Antigen PresentationAntigen-Presenting CellsFood HypersensitivityImmune ToleranceIntestinesAnimalsAntigensCell CommunicationDendritic CellsInflammationMiceMice, Inbred C57BLNuclear Receptor Subfamily 1, Group F, Member 3Th2 CellsT-Lymphocytes, RegulatoryAntigensNuclear Receptor Subfamily 1, Group F, Member 3
Identifiers
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.