ArticlePloS one2024
Significant association between three atherosclerosis indexes and stroke risk.
Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Novel lipid and obesity indices with new-onset stroke among adults aged 50 years and older in England.Scientific reports · 2026Article
- Association of the atherogenic index of plasma and a novel triglyceride-glucose-body shape index with stroke: insights from NHANES and machine learning approaches.BMC cardiovascular disorders · 2026Article
- Atherogenic index of plasma in stroke: A comprehensive review of its diagnostic, prognostic, and pathophysiological significance.World journal of clinical cases · 2026Review
- The association between different lipid indices and hyperuricemia in older adults: a cross-sectional study.Lipids in health and disease · 2025Article
- Correlation between Castelli risk index-I and female infertility: A cross-sectional study.Lipids in health and disease · 2025Article
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5 authors.
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Abstract
backgroundTo evaluate the associations of three atherosclerosis indexes with stroke in a population aged 65 years and older.
methodsA sample was obtained from wave 2011 to wave 2015 of the China Health and Retirement Longitudinal Study. Multivariate logistic regression models were used to estimate odds ratios (ORs) with 95% confidence intervals (CIs) for stroke in the quartiles of three atherosclerosis indexes, and restricted cubic splines were constructed.
resultsFour hundred and fifty-four of the 21,913 eligible participants had stroke. After multivariate adjustments and with respect to the lowest quartiles, the ORs (95% CIs) of stroke in the highest quartiles of the atherogenic index of plasma (AIP), the Castelli risk index I (CRI-I), and the Castelli risk index II (CRI-II) were 1.35 (0.99-1.83), 1.52 (1.13-2.06), and 1.40 (1.05-1.86), respectively. When assessed as a continuous exposure, per-unit increases in the AIP, CRI-I, and CRI-II were independently associated with a 49% (OR: 1.49, 95% CI: 1.07-2.08), 6% (OR: 1.06, 95% CI: 1.02-1.11), and 14% (OR: 1.14, 95% CI: 1.03-1.27) increase in the risk of stroke, respectively.
conclusionThe three atherosclerosis indexes studied-the AIP, CRI-I, and CRI-II-were found to be predictors of stroke in a Chinese population.
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