Evidence map›Paper›PMID 39699766›Full record

ArticleJournal of autism and developmental disorders2024

Decreasing Agitation in Neurodiverse Patients with Mental Health Concerns.

Diana Hou Yan, Avery Jeon, Yunfai Ng, Alexa Rivera, Lauren Donnelly, Lorien Baker, Manuela P Zisu, Czer Anthoney Lim

Abstract read
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In one paragraph

Article in Journal of autism and developmental disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Diana Hou YanDepartment of Emergency Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. diana.yan@mountsinai.org.ORCID http://orcid.org/0000-0003-1604-9610
Avery JeonSchool of General Studies, Columbia University, New York, NY, USA.
Yunfai NgDepartment of Emergency Medicine, Mount Sinai Morningside/West, New York, NY, USA.
Alexa RiveraDepartment of Psychiatry, Mount Sinai Hospital, New York, NY, USA.
Lauren DonnellyDepartment of Child and Adolescent Psychiatry, Hassenfeld Children's Hospital at NYU Langone, New York, NY, USA.
Lorien BakerDepartment of Child and Adolescent Psychiatry, Hassenfeld Children's Hospital at NYU Langone, New York, NY, USA.
Manuela P ZisuDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Czer Anthoney LimDepartment of Emergency Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.

Funding

Conduits: Mount Sinai Health System Translational Science HubUL1TR004419 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Rosalind J Wright · 2022 to 2026
$46.4M
NCATS NIH HHS UL1TR004419New York State Office of Mental Health OMH01-T22776GG-3650000
6 · The paper itself

Abstract

purposeChildren and adolescents are experiencing a mental health crisis. Neurodiverse patients have high rates of mental health conditions and worse outcomes. To address this disparity, the Autism Spectrum Disorder Care Pathway was applied to a pediatric emergency department (PED) and Observation Unit (OU) in order to decrease agitation experienced by these patients.

methodsThis prospective cohort study was in a community-based PED and OU from June 2023 to February 2024. A medical education curriculum consisting of a multidisciplinary champion training and toolkit rollout was completed. Agitation was measured by the Behavioral Activity Rating Scale. The primary aim was to decrease frequency of agitation experienced by neurodiverse patients at any point in the PED/OU. The secondary outcome was to decrease pharmacologic intervention and physical restraint use.

resultsWe captured data from a total of 45 patients, with 19 baseline patients and 26 patients in the intervention group. At baseline, 9 out of 19 (47%) patients experienced agitation at some point in their PED/OU stay. After implementation of the curriculum, agitation levels decreased to 6 out of 26 (23%) patients (p = 0.04). Inter-rater reliability was 0.95. There were 3 incidences of pharmacologic intervention and no physical restraint use.

conclusionsThis pilot medical education curriculum for PED and OU staff members decreased agitation in neurodiverse patients who presented for mental health complaints. This study is the foundation for expansion of the curriculum for use in general emergency departments.

Indexed as

AgitationAutism spectrum disorder clinical pathwayNeurodiverse patientsPediatric emergency department

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.