Evidence map›Paper›PMID 39699631›Full record

SynthesisEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025

Petrous bone cholesteatoma (PBC): report of 94 cases of PBC with focus on intraoperative endoscopic assistance, and systematic review of the literature.

Monica Rueda Vega, Carolina López Granados, Carlos Martín Oviedo, Ignacio Arístegui Torrano, Miguel Arístegui Ruiz

Abstract readSystematic ReviewObservational Study
PubMed Publisher
In one paragraph

Synthesis in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Monica Rueda VegaDepartment of Otolaryngology-Head and Neck Surgery, Hospital General Universitario Gregorio Marañón, C/Doctor Esquerdo, 46. 3rd Floor, 28007, Madrid, CP, Spain. monica.ruedavega@gmail.com.ORCID https://orcid.org/0000-0002-6501-2833
Carolina López GranadosDepartment of Otolaryngology-Head and Neck Surgery, Hospital General Universitario Gregorio Marañón, C/Doctor Esquerdo, 46. 3rd Floor, 28007, Madrid, CP, Spain.
Carlos Martín OviedoDepartment of Otolaryngology-Head and Neck Surgery, Hospital General Universitario Gregorio Marañón, C/Doctor Esquerdo, 46. 3rd Floor, 28007, Madrid, CP, Spain.
Ignacio Arístegui TorranoDepartment of Otolaryngology-Head and Neck Surgery, Hospital General Universitario Gregorio Marañón, C/Doctor Esquerdo, 46. 3rd Floor, 28007, Madrid, CP, Spain.
Miguel Arístegui RuizDepartment of Otolaryngology-Head and Neck Surgery, Hospital General Universitario Gregorio Marañón, C/Doctor Esquerdo, 46. 3rd Floor, 28007, Madrid, CP, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study is to assess the clinical characteristics, classification, surgical approaches, interventional strategies, and treatment outcomes of patients with petrous bone cholesteatoma (PBC).

methodsObservational retrospective study of patients with PBC managed by the senior author of this paper between 1995 and 2024 in a tertiary referral center. A literature review was made, identifying 16 articles. Clinical presentations, Sanna's classification, pre- and post-surgical facial function and audiometry, surgical approach and intraoperative endoscopic assistance, postoperative complications, and recurrence rates were reported.

resultsWe report on a large series of 94 cases managed by the senior author. The most common type was supralabyrinthine PBCs (40.43%; 38 cases), followed by massive (18.09%; 17). Hearing loss was present in almost all the patients (98.91%). The most frequent approaches were the modified translabyrinthine approach (24.51%; 25), the subtotal petrosectomy (22.55%; 23) and the transotic approach (18.63%; 19). In 11 patients the approach was assisted by the use of an endoscope. Recurrence of PBC was identified in 8 cases (8.51%) that were surgically resolved. Additionally, we report a review of the literature (16 articles).

conclusionsWe focus on the introduction of endoscopic assisted techniques that may help in reducing the rate of residual and avoid rerouting of the facial nerve. At the same time, we encourage techniques that include elimination of the middle ear through a subtotal petrosectomy, as they are essential to protect vital structures that have been exposed by the disease or by the surgical technique.

Indexed as

CholesteatomaCholesteatoma, Middle EarEndoscopyPetrous BoneAdolescentAdultAgedChildFemaleHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesTreatment OutcomeYoung AdultEndoscopic ear surgeryPetrous bone cholesteatomaRecurrencesSanna’s classificationSubtotal petrosectomyTransotic approach

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.