Evidence map›Paper›PMID 39699257›Full record

ReviewThe Australian & New Zealand journal of obstetrics & gynaecology2025

The impact of using cannabis during pregnancy on the infant and mother: An overview of systematic reviews, evidence map, targeted updates, and de novo synthesis.

Zachary Munn, Danielle Pollock, Jennifer Stone, Sabira Hasanoff, Andrea Gordon, Carrie Price, Michael Stark, Timothy Hugh Barker

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The Australian & New Zealand journal of obstetrics & gynaecology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zachary MunnHealth Evidence Synthesis, Recommendations and Impact (HESRI), School of Public Health, University of Adelaide, Adelaide, Australia.
Danielle PollockHealth Evidence Synthesis, Recommendations and Impact (HESRI), School of Public Health, University of Adelaide, Adelaide, Australia.
Jennifer StoneJBI, School of Public Health, University of Adelaide, Adelaide, Australia.
Sabira HasanoffHealth Evidence Synthesis, Recommendations and Impact (HESRI), School of Public Health, University of Adelaide, Adelaide, Australia.ORCID 0000-0001-7246-0485
Andrea GordonThe Robinson Research Institute, University of Adelaide, Adelaide, Australia.
Carrie PriceAlbert S. Cook Library, Towson University, Maryland, USA.
Michael StarkThe Robinson Research Institute, University of Adelaide, Adelaide, Australia.
Timothy Hugh BarkerHealth Evidence Synthesis, Recommendations and Impact (HESRI), School of Public Health, University of Adelaide, Adelaide, Australia.

Funding

National Health and Medical Research Council Ideas Grant APP2011958National Health and Medical Research Council Investigator Grant 1195676NSW Health
6 · The paper itself

Abstract

backgroundCannabis use during pregnancy is becoming more prevalent. While numerous studies have explored the relationship of cannabis use during pregnancy and outcomes for mothers and infants, uncertainty remains regarding the impact of cannabis use on pregnancy complications and later-life outcomes for offspring.

aimsTo produce a summary of the short and long-term effects of prenatal cannabis exposure on fetal growth and development, neonatal conditions, later-life, and maternal outcomes. MATERIALS AND

methodsAn overview of systematic reviews, an evidence and gap map, targeted updates of previous reviews, and de novo evidence synthesis was conducted. The databases searched include PubMed (National Center for Biotechnology Information); MEDLINE (Ovid); Embase (Ovid) and CINAHL with Full Text (EBSCO). Assessment of risk of bias was conducted in duplicate for all studies. Relevant studies were coded and are presented as an evidence and gap map. Where possible, meta-analyses were conducted with a narrative synthesis of the results. Primary studies and systematic reviews examining the relationship between cannabis consumption in pregnancy and the effect on fetal/child development, antenatal, and obstetric outcomes during pregnancy were eligible for inclusion.

resultsThere were 89 studies/reviews eligible for inclusion in this review. There was a potentially harmful impact of prenatal cannabis exposure on all fetal growth and development outcomes, some neonatal outcomes, some later-life outcomes, and some maternal outcomes. The evidence regarding other neonatal conditions, later-life, and maternal outcomes was mixed.

conclusionsThe evidence suggests cannabis should be avoided during pregnancy.

Indexed as

CannabisFetal DevelopmentMarijuana UsePregnancy ComplicationsPrenatal Exposure Delayed EffectsFemaleHumansInfant, NewbornPregnancyPregnancy OutcomeSystematic Reviews as Topicfemalefetal developmenthallucinogenshumansinfantnewbornsystematic reviews as topic

Identifiers

PMID39699257
PMCPMC12282043

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.