Evidence map›Paper›PMID 39699250›Full record

ArticleMedical physics2025

Personalized deep learning auto-segmentation models for adaptive fractionated magnetic resonance-guided radiation therapy of the abdomen.

Maria Kawula, Sebastian Marschner, Chengtao Wei, Marvin F Ribeiro, Stefanie Corradini, Claus Belka, Guillaume Landry, Christopher Kurz

Abstract read
In one paragraph

Article in Medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maria KawulaDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
Sebastian MarschnerDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
Chengtao WeiDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
Marvin F RibeiroDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
Stefanie CorradiniDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
Claus BelkaDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
Guillaume LandryDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
Christopher KurzDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.

Funding

Wilhelm Sander-Stiftung 2019.162.2
6 · The paper itself

Abstract

backgroundManual contour corrections during fractionated magnetic resonance (MR)-guided radiotherapy (MRgRT) are time-consuming. Conventional population models for deep learning auto-segmentation might be suboptimal for MRgRT at MR-Linacs since they do not incorporate manual segmentation from treatment planning and previous fractions. PURPOSE: In this work, we investigate patient-specific (PS) auto-segmentation methods leveraging expert-segmented planning and prior fraction MR images (MRIs) to improve auto-segmentation on consecutive treatment days. MATERIALS AND

methodsData from 151 abdominal cancer patients treated at a 0.35 T MR-Linac (151 planning and 215 fraction MRIs) were included. Population baseline models (BMs) were trained on 107 planning MRIs for one-class segmentation of the aorta, bowel, duodenum, kidneys, liver, spinal canal, and stomach. PS models were obtained by fine-tuning the BMs using the planning MRI (

results

conclusionPersonalized auto-segmentation models outperformed the population BMs. In most cases,

Indexed as

AbdomenAbdominal NeoplasmsDeep LearningDose Fractionation, RadiationImage Processing, Computer-AssistedMagnetic Resonance ImagingPrecision MedicineRadiotherapy, Image-GuidedAutomationHumansMaleRadiotherapy Planning, Computer-Assistedauto‐segmentationMR‐Linacpatient‐specific transfer learning

Identifiers

PMID39699250
PMCPMC11972049

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.