Evidence map›Paper›PMID 39699186›Full record

ArticlemSphere2025

Comparative analysis of the human microbiome from four different regions of China and machine learning-based geographical inference.

Yinlei Lei, Min Li, Han Zhang, Yu Deng, Xinyu Dong, Pengyu Chen, Ye Li, Suhua Zhang, Chengtao Li, Shouyu Wang and 1 more

Abstract readComparative Study
In one paragraph

Article in mSphere, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Forensic genetics in the omics era.Nature reviews. Genetics · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yinlei Lei *Shanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Academy of Forensic Sciences, Key Laboratory of Forensic Science, Ministry of Justice, Shanghai, China.ORCID 0009-0008-0944-9572
Min Li *School of Clinical and Basic Medical Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China.
Han ZhangInstitute of Forensic Science, Fudan University, Shanghai, China.
Yu DengShanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Academy of Forensic Sciences, Key Laboratory of Forensic Science, Ministry of Justice, Shanghai, China.
Xinyu DongMinhang Branch of Shanghai Public Security Bureau, Shanghai, China.
Pengyu ChenDepartment of Forensic Medicine, Zunyi Medical University, Zunyi, China.
Ye LiDepartment of Forensic Medicine, School of Basic Medical Sciences, Xinjiang Medical University, Urumqi, China.
Suhua ZhangInstitute of Forensic Science, Fudan University, Shanghai, China.
Chengtao LiInstitute of Forensic Science, Fudan University, Shanghai, China.
Shouyu WangDepartment of Forensic Medicine, Shanghai Medical College, Fudan University, Shanghai, China.ORCID 0000-0002-6082-2028
Ruiyang TaoShanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Academy of Forensic Sciences, Key Laboratory of Forensic Science, Ministry of Justice, Shanghai, China.ORCID 0000-0002-7580-2062

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human microbiome, the community of microorganisms that reside on and inside the human body, is critically important for health and disease. However, it is influenced by various factors and may vary among individuals residing in distinct geographic regions. In this study, 220 samples, consisting of sterile swabs from palmar skin and oral and nasal cavities were collected from Chinese Han individuals living in Shanghai, Chifeng, Kunming, and Urumqi, representing the geographic regions of east, northeast, southwest, and northwest China. The full-length 16S rRNA gene of the microbiota in each sample was sequenced using the PacBio single-molecule real-time sequencing platform, followed by clustering the sequences into operational taxonomic units (OTUs). The analysis revealed significant differences in microbial communities among the four regions.

Indexed as

BacteriaMachine LearningMicrobiotaAdultChinaDNA, BacterialFemaleHandHumansMaleMiddle AgedMouthNasal CavityPhylogenyRNA, Ribosomal, 16SSequence Analysis, DNADNA, BacterialRNA, Ribosomal, 16S16S rRNAgeographic regionshuman microbiomemachine learning

Identifiers

PMID39699186
PMCPMC11774049

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.