Evidence map›Paper›PMID 39698880›Full record

ArticleJournal of applied clinical medical physics2025

Dosimetric comparison of M6 CyberKnife plans optimized with Precision and RayStation 12A treatment planning systems.

Maude Gondré, Véronique Vallet, Jean Bourhis, François Bochud, Raphael Moeckli

Abstract readComparative Study
In one paragraph

Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Maude GondréInstitute of Radiation Physics, Lausanne University Hospital and Lausanne University, Lausanne, Switzerland.ORCID https://orcid.org/0009-0000-4736-7799
Véronique ValletInstitute of Radiation Physics, Lausanne University Hospital and Lausanne University, Lausanne, Switzerland.
Jean BourhisRadio-Oncology Department, Lausanne University Hospital and Lausanne University, Lausanne, Switzerland.
François BochudInstitute of Radiation Physics, Lausanne University Hospital and Lausanne University, Lausanne, Switzerland.
Raphael MoeckliInstitute of Radiation Physics, Lausanne University Hospital and Lausanne University, Lausanne, Switzerland.ORCID https://orcid.org/0000-0002-5885-934X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTreatment planning for CyberKnife (CK) (Accuray, USA) can be performed with Precision (Accuray, USA) or RayStation (RS) (RaySearch Laboratories, Sweden) treatment planning systems (TPS). RaySearch recently released a new version of the CK module in RS 12A. The objective of the study was to compare plan quality between RS 12A and Precision.

methodsFifty nine plans were optimized with both TPS and compared; 39 were for brain metastases and 20 were for vertebral metastases. To avoid bias in plan comparison, Precision plans were recomputed in RS with the dose algorithm and beam model of RS, and then compared to RS plans. The comparison was divided into 3 parts in order to reflect the potential of RS and the differences with Precision, in terms of technical aspects of delivery efficiency and dose distribution. We compared the dose to the target and to the organs at risk (OAR), the conformity index (CI), the gradient, as well as the number of monitor units (MU), and the number of beams and nodes. Finally, a global plan quality index (PQI) was calculated.

resultsRS plans showed an equivalent target coverage for brain metastases but worse for vertebrae. OAR sparing was improved in RS but with a lower CI compared to Precision. Using an appropriate planning methodology in RS, plans with comparable quality to Precision could be obtained, but at the cost of a longer optimization time. The PQI obtained with RS was better than Precision, except for some brain cases.

conclusionRS is an adequate alternative for CK planning as it is possible to obtain plan quality comparable to Precision. However, the optimization time is longer compared to Precision and more attention must be paid to the choice of the initial conditions in terms of the number of beams and nodes.

Indexed as

AlgorithmsBrain NeoplasmsOrgans at RiskRadiosurgeryRadiotherapy Planning, Computer-AssistedSpinal NeoplasmsHumansRadiometryRadiotherapy DosageRadiotherapy, Intensity-ModulatedCyberKnifeoptimizationtreatment planning system

Identifiers

PMID39698880
PMCPMC11905244

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