ArticleQuantitative imaging in medicine and surgery2024
Value of two-dimensional speckle-tracking echocardiography in evaluation of cardiac function in small fetuses.
Article in Quantitative imaging in medicine and surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Inclusion of Speckle Tracking Echocardiography Analysis in the Management of Intrauterine Growth Restrictions-Literature Review and Case Reports.Journal of clinical medicine · 2025Review
- Fetal heart quantification ultrasound technology for the quantitative analysis of fetal cardiac morphology and function in hypertensive disorders of pregnancy.Quantitative imaging in medicine and surgery · 2025Article
- Advances in cardiac ultrasound speckle tracking technology for assessing left ventricular systolic function after adjuvant radiotherapy following breast-conserving surgery for breast cancer.American journal of translational research · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Small fetuses include constitutional small for gestational age (SGA) and fetal growth-restricted (FGR) fetuses. Various adverse intrauterine environments can lead to FGR which has higher risk of abnormal perinatal outcome. The fetal heart is very sensitive to the effects of a negative intrauterine environment. Therefore, we used two-dimensional speckle-tracking echocardiography (2D-STE) to evaluate heart function and find more sensitive indicators of pregnancy outcomes of small fetuses. Methods: This prospective cohort study was performed at West China Second Hospital of Sichuan University between July 2023 and December 2023. We prospectively enrolled small fetuses with an estimated weight or abdominal circumference below the 10th percentile for gestational age and controls matched for gestational age. 2D-STE was performed to obtain information on left ventricular function systolic function and strain parameters, including ejection fraction (EF), myocardial global circumferential strain (myoGCS), myocardial global longitudinal strain (myoGLS), endocardial global circumferential strain (endoGCS), endocardial global longitudinal strain (endoGLS), and global radial strain (GRS). The baseline characteristics and various cardiac parameters were compared between the groups. Then, we analyzed the predictive performance of cardiac parameters, and pulsatility index of umbilical artery and middle cerebral artery (UA-PI, MCA-PI) for adverse pregnancy outcomes. Results: A total of 61 small fetuses and 34 gestational age-matched control fetuses were studied ultimately. The value of EF, myoGCS, myoGLS,endoGCS, endoGLS, and GRS were 44.85±10.04, -11.89±4.24, -9.26±4.24, -22.68±6.24, -13.53±6.67, and 24.98±12.44, respectively, in the FGR group, the absolute values of which were significantly lower than in the SGA group (53.28±6.70, -14.42±4.31, -12.63±4.11, -27.29±7.25, -17.71±5.58, and 33.37±9.33, respectively) and the control group (55.46±6.94, -14.93±4.77, -16.15±3.84, -27.69±6.46, -20.55±4.42, and 36.87±12.69, respectively) (P<0.05). The absolute myoGLS and endoGLS values were significantly lower in the SGA group than in the control group (P<0.05). Combination of endoGLS and UA-PI could represent a new predictor to predict the adverse pregnancy outcomes, and the receiver operating characteristic (ROC) curve exhibited a considerably higher area under the curve (AUC) than either one alone (AUC of 0.75 Conclusions: The layer-specific strain technique in 2D-STE is a sensitive tool for evaluation of left ventricular myocardial deformation in the heart of small fetuses, and can be used to identify the changes of cardiac function between FGR and SGA. Moreover, the combination of endoGLS and UA-PI as a new parameter may have better performance in predicting pregnancy outcome of small fetuses.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.