ArticleQuantitative imaging in medicine and surgery2024
Assessing regional homogeneity and cognitive function alterations in pediatric brain tumor patients: a resting-state functional magnetic resonance imaging study.
Article in Quantitative imaging in medicine and surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Theoretical, Technical, and Analytical Foundations of Task-Based and Resting-State Functional Magnetic Resonance Imaging (fMRI)-A Narrative Review.Biomedicines · 2026Review
- Insights into structural deviations in attention deficit hyperactivity disorder (ADHD) and comorbidities using big data-derived brain charts: a cross-sectional study.Quantitative imaging in medicine and surgery · 2025Article
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7 authors.
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Abstract
Background: Cognitive impairment mechanisms in children with preoperative brain tumors are not well understood. This study aimed to determine the correlation between the changes of resting-state functional magnetic resonance imaging (rs-fMRI) and the fourth edition of the Wechsler Intelligence Scale for Children (WISC-IV) in patients with brain tumors before surgery and in healthy controls (HCs). Methods: rs-fMRI data were acquired using 3-T magnetic resonance imaging (MRI) scanners for 21 patients with pediatric brain tumor and 19 age- and gender-matched HCs. The data of WISC-IV were collected by psychiatrists. We used chi-square tests and two-sample Results: The ReHo values were significantly decreased in the left anterior cingulate (T=-4.391) and right middle frontal gyrus (MFG) (T=-5.130) in patients compared to controls. Notably, ReHo values in the right MFG showed a positive correlation with the Perceptual Reasoning Index (R=0.471; P=0.031) and Working Memory Index (R=0.531; P=0.013) of the WISC-IV. Conclusions: The study identified significant ReHo alterations in patients with pediatric brain tumor, primarily in brain regions associated with cognitive processing, and revealed a positive correlation between these alterations and specific cognitive functions. These findings contribute to understanding cognitive impairments in this patient group and suggest potential areas for targeted intervention.
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