ReviewQuantitative imaging in medicine and surgery2024
Application of cryoablation in animal models of bladder and muscle-invasive bladder cancer: a narrative review of current status and future perspectives.
Review in Quantitative imaging in medicine and surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Objective: In patients diagnosed with bladder cancer (BC), muscle-invasive bladder cancer (MIBC) accounts for 25%, including tumors invading the intrinsic muscle layer (T2), surrounding tissues of the bladder (T3), or adjacent pelvic organs/structures (T4). Cryoablation promises to be a novel interventional oncology technique, which effectively induces cellular destruction through freezing and thawing cycles. In addition to the direct tumor-killing effect, it also has a tumor-immune effect. Although this technique has been widely used among solid tumors, including liver, lung, and breast cancer, there have been few studies on tumors of hollow organs, such as BC. Thus, we summarized the application of cryoablation in BC according to reports from animal models and clinical studies and predicted the future direction of this treatment. Methods: A literature search was performed in the PubMed database for articles published in English between 2001 and 2024. The keywords used were: "muscle-invasive bladder cancer", "bladder cancer", "cryoablation", and "cryosurgery". In total, 42 articles were included. We also gathered imaging data from the Minimally Invasive Tumor Therapies Center of Beijing Hospital. Key Content and Findings: Cryoablation for MIBC is a relatively safe, feasible, and promising minimally invasive treatment technique. Cryoablation as an adjuvant therapy with transurethral resection of bladder tumor (TURBT) is feasible and safe in T2 MIBC. It is able to achieve satisfactory local control. In T3-T4 MIBC, cryoablation can serve as a palliative treatment to reduce the tumor burden, but needs to be combined with other treatments to improve the prognosis. Conclusions: This review presents a comprehensive overview of the current state and future perspectives of cryoablation in animal models of BC and MIBC, which might set a strong foundational knowledge base. Moreover, this novel approach could potentially revolutionize treatment paradigms if further validated.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.