Evidence map›Paper›PMID 39698501›Full record

ArticleFrontiers in network physiology2024

Significant nocturnal wakefulness after sleep onset in metabolic dysfunction-associated steatotic liver disease.

Sofia Schaeffer, Andrijana Bogdanovic, Talitha Hildebrandt, Emilio Flint, Anne Geng, Sylvia Pecenko, Paul Lussier, Michael A Strumberger, Martin Meyer, Jakob Weber and 3 more

Abstract read
In one paragraph

Article in Frontiers in network physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. The Beauty Sleep to Keep a Healthy Liver.International journal of molecular sciences · 2025
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sofia Schaeffer *Department of Biomedicine and Department of Clinical Research, University of Basel, Basel, Switzerland.
Andrijana Bogdanovic *Department of Biomedicine and Department of Clinical Research, University of Basel, Basel, Switzerland.
Talitha HildebrandtDepartment of Biomedicine and Department of Clinical Research, University of Basel, Basel, Switzerland.
Emilio FlintDepartment of Biomedicine and Department of Clinical Research, University of Basel, Basel, Switzerland.
Anne GengDepartment of Biomedicine and Department of Clinical Research, University of Basel, Basel, Switzerland.
Sylvia PecenkoDepartment of Biomedicine and Department of Clinical Research, University of Basel, Basel, Switzerland.
Paul LussierDepartment of Biomedicine and Department of Clinical Research, University of Basel, Basel, Switzerland.
Michael A StrumbergerCentre for Chronobiology, Psychiatric Hospital of the University of Basel, Basel, Switzerland.
Martin MeyerCentre for Chronobiology, Psychiatric Hospital of the University of Basel, Basel, Switzerland.
Jakob WeberNovoLytiX GmbH, Witterswil, Switzerland.
Markus H HeimDepartment of Biomedicine and Department of Clinical Research, University of Basel, Basel, Switzerland.
Christian CajochenCentre for Chronobiology, Psychiatric Hospital of the University of Basel, Basel, Switzerland.
Christine BernsmeierDepartment of Biomedicine and Department of Clinical Research, University of Basel, Basel, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic dysfunction-associated steatotic liver disease (MASLD) is a multisystemic disease with a multifactorial pathogenesis involving dietary, environmental, and genetic factors. Previous mouse models suggested that circadian misalignment may additionally influence its development as it influences metabolism in diverse organs including the liver. Further, data from sleep questionnaires proved sleep-wake disruption in patients with MASLD. We objectively assessed sleep-wake rhythms in patients with biopsy-proven MASLD (n = 35) and healthy controls (HC, n = 16) using actigraphy 24/7 for 4 weeks. With the aim to re-align sleep rhythms a single standardized sleep hygiene education session was performed after 2 weeks. Actigraphy data revealed that MASLD patients had more awakenings per night (MASLD vs. HC 8.5 vs. 5.5,

Indexed as

actigraphycircadian misalignmentcircadian rhythmMASLDsleep hygiene education

Identifiers

PMID39698501
PMCPMC11652136

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.