Evidence map›Paper›PMID 39698368›Full record

ArticleKidney international reports2024

Long-Term Kidney Outcome of Lupus Nephritis by Renal Response Status.

Desmond Yat Hin Yap, Xiaomeng Xu, Patricia C Juliao, Colin S O Tang, Laura Ng, Dominique Milea, Tak Mao Chan

Abstract read
In one paragraph

Article in Kidney international reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Observational
  7. Lupus nephritis.Nature reviews. Disease primers · 2025
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Desmond Yat Hin YapSchool of Clinical Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong, China.
Xiaomeng XuGCI VEO, GSK, Singapore.
Patricia C JuliaoImmunology and Opportunistic Epidemiology, VEO, GSK, Collegeville, Pennsylvania, USA.
Colin S O TangSchool of Clinical Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong, China.
Laura NgGSK HK, Hong Kong.
Dominique MileaGCI VEO, GSK, Singapore.
Tak Mao ChanSchool of Clinical Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Limited evidence exists that clinical trial treatment response criteria predict long-term outcomes in Asian patients with lupus nephritis (LN). Methods: This retrospective analysis of prospectively collected data from the Hong Kong Queen Mary Hospital Cohort categorized adults with biopsy-proven LN (Class III, IV, V, or mixed [III ± V, IV ± V]) after standard treatment for 2 years postbiopsy and immunosuppression induction according to modified primary efficacy renal response (mPERR: estimated glomerular filtration rate [eGFR] ≥ 60 ml/min per 1.73 m Results: Of the 176 Chinese patients, 64.2% achieved mPERR and 43.8% achieved mCRR at 2 years postbiopsy. After mean follow-up of 15.3 years, significantly higher proportions of mPERR and mCRR responders versus nonresponders achieved long-term kidney survival (mPERR: 85.8% vs. 71.4%; Conclusion: In Chinese patients with LN, mPERR and mCRR at 2 years postbiopsy predict superior long-term kidney outcomes and lower CKD progression risk.

Indexed as

chronic kidney diseaseend-stage kidney diseaselupus erythematosus, systemiclupus nephritisrenal response

Identifiers

PMID39698368
PMCPMC11652096

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.