Evidence map›Paper›PMID 39698163›Full record

ArticleThe World Allergy Organization journal2024

Fel d 1 specific IgE measurement for dog exclusive owners co-sensitized to dog and cat.

Lin Liang, Ah-Reum Hwang, Yoon Ji Shin, Kyoung Yong Jeong, Kyung Hee Park, Jae-Hyun Lee, Jung-Won Park

Abstract read
In one paragraph

Article in The World Allergy Organization journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lin LiangGraduate School of Medicine, Yonsei University College of Medicine, Seoul, South Korea.
Ah-Reum HwangInstitute of Allergy, Yonsei University College of Medicine, Seoul, South Korea.
Yoon Ji ShinInstitute of Allergy, Yonsei University College of Medicine, Seoul, South Korea.
Kyoung Yong JeongInstitute of Allergy, Yonsei University College of Medicine, Seoul, South Korea.
Kyung Hee ParkInstitute of Allergy, Yonsei University College of Medicine, Seoul, South Korea.
Jae-Hyun LeeInstitute of Allergy, Yonsei University College of Medicine, Seoul, South Korea.
Jung-Won ParkInstitute of Allergy, Yonsei University College of Medicine, Seoul, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The diagnosis of the culprit allergen depends on exposure, symptoms at exposure, and the presence of specific IgE (sIgE). Pet allergens are sticky and can sensitize individuals without adoption history. Exclusive dog owners frequently exhibit both dog (e5) and cat dander sIgE (e1). We assessed whether the measurement of Fel d 1 sIgE (e94) can discriminate true cat sensitization from false positivity by cross-reactivity in the exclusive dog owners. Methods: Thirty-one patients with respiratory allergies who exclusively owned dogs were enrolled for this study. e5, e1, and e94 were measured with ImmunoCAP. ELISA inhibition was performed to assess cross-reactivity. Results: About 81% of patients (25/31) were both e5 and e1 positive, and 8 were also positive for e94. In the e94 positive, cat dander exhibited higher maximum inhibition of cat sIgE (94% vs 88%) and demonstrated lower IC Conclusions: Genuine co-sensitization to cats is notable even in individuals who exclusively own dogs. Positive e94 results could discriminate authentic cat sensitization from false positivity by cross-reactivity in these patients, underscoring the importance of comprehensive allergy assessment.

Indexed as

CatCross-reactivityDogFel d 1

Identifiers

PMID39698163
PMCPMC11652762

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.