Evidence map›Paper›PMID 39698025›Full record

ArticleExtracellular vesicles and circulating nucleic acids2023

Inhibition of osteosarcoma by European Mistletoe derived val-miR218.

Wenyan Xie, Catharina Delebinski, Dennis Gürgen, Maik Schröder, Georg Seifert, Matthias F Melzig

Abstract read
In one paragraph

Article in Extracellular vesicles and circulating nucleic acids, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. MISTOSUS: a phase II trial ofFuture oncology (London, England) · 2026
    Trial
  2. Translational cancer research · 2026
    Article
  3. Article
  4. Mistletoe in Cancer Cell Biology: Recent Advances.Current issues in molecular biology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wenyan XieInstitute of Pharmacy, Freie Universität Berlin, Berlin 14195, Germany.
Catharina DelebinskiDepartment of Pediatric Oncology/Hematology, Otto-Heubner-Centre for Pediatric and Adolescent Medicine (OHC), Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin 13353, Germany.
Dennis GürgenEPO GmbH Berlin, Berlin 13353, Germany.
Maik SchröderDepartment of Pediatric Oncology/Hematology, Otto-Heubner-Centre for Pediatric and Adolescent Medicine (OHC), Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin 13353, Germany.
Georg SeifertDepartment of Pediatric Oncology/Hematology, Otto-Heubner-Centre for Pediatric and Adolescent Medicine (OHC), Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin 13353, Germany.
Matthias F MelzigInstitute of Pharmacy, Freie Universität Berlin, Berlin 14195, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: In recent years, there has been a growing interest in the therapeutic potential of plant-derived miRNAs, which have been considered new bioactive ingredients in medicinal plants. Methods: The anti-cancer effects of miRNAs from Results: Among these abundant miRNAs in Conclusion: This study demonstrated the significant potential of val-miR218 regarding proliferation inhibition in various tumor cell lines

Indexed as

medicinal plantsmiRNAsmistletoeosteosarcomaViscum album L

Identifiers

PMID39698025
PMCPMC11651123

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.