Evidence map›Paper›PMID 39697634›Full record

ArticleExtracellular vesicles and circulating nucleic acids2024

Transfer of

Hannah M Nelson, Shimian Qu, Liyu Huang, Muhammad Shameer, Kevin C Corn, Sydney N Chapman, Nicole L Luthcke, Sara A Schuster, Tellie D Stamaris, Lauren A Turnbull and 11 more

Abstract read
In one paragraph

Article in Extracellular vesicles and circulating nucleic acids, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Hannah M NelsonLaboratory of James G. Patton, Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA.
Shimian QuLaboratory of James G. Patton, Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA.
Liyu HuangLaboratory of James G. Patton, Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA.
Muhammad ShameerLaboratory of James G. Patton, Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA.
Kevin C CornLaboratory of Marjan Rafat, Department of Biomedical Engineering, Vanderbilt University, Nashville, TN 37232, USA.
Sydney N ChapmanLaboratory of James G. Patton, Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA.
Nicole L LuthckeLaboratory of James G. Patton, Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA.
Sara A SchusterLaboratory of James G. Patton, Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA.
Tellie D StamarisLaboratory of James G. Patton, Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA.
Lauren A TurnbullLaboratory of James G. Patton, Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA.
Lucas L GuyLaboratory of James G. Patton, Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA.
Xiao LiuLaboratory of Qi Liu, Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Danielle L MichellLaboratory of Kasey C. Vickers, Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Elizabeth M SemlerLaboratory of Kasey C. Vickers, Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Kasey C VickersLaboratory of Kasey C. Vickers, Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Qi LiuLaboratory of Qi Liu, Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Jeffrey L FranklinDepartment of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, TN 37235, USA.
Alissa M WeaverLaboratory of Alissa M. Weaver, Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37235, USA.
Marjan RafatLaboratory of Marjan Rafat, Department of Biomedical Engineering, Vanderbilt University, Nashville, TN 37232, USA.
Robert J CoffeyLaboratory of Robert J. Coffey, Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
James G PattonLaboratory of James G. Patton, Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA.

Funding

Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Non-coding RNA & Bioinformatics CoreP01HL116263 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI LINTON, MACRAE F · 2014 to 2025
$24.7M
Vanderbilt-Ingram Cancer Center SPORE in Gastrointestinal CancerP50CA236733 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Robert J. Coffey · 2019 to 2026
$19.6M
Roles for Supermeres in CRC ProgressionP01CA229123 · NCI · VANDERBILT UNIVERSITY · PI Alissa M Weaver · 2020 to 2026
$12.9M
Integrated approach to study early and late events in colonic neoplasia: mouse to manR35CA197570 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Robert J. Coffey · 2017 to 2026
$9.4M
Integrated Training in Engineering and DiabetesT32DK101003 · NIDDK · VANDERBILT UNIVERSITY · PI Jamey D. Young · 2014 to 2026
$3.9M
Uncovering exRNA and protein determinants of secreted vesicle heterogeneity by flow cytometric purification of vesicle subsets from cells and plasmaUH3CA241685 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CHAREST, ALAIN, COFFEY, ROBERT J. · 2021 to 2022
$2.1M
Novel functions of plasminogen and its diverse cargo in bloodR01HL173598 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Kasey C Vickers · 2024 to 2026
$1.1M
American Heart Association-American Stroke Association 971070NCI NIH HHS P01 CA229123NCI NIH HHS P50 CA236733NCI NIH HHS R35 CA197570NCI NIH HHS UH3 CA241685NHLBI NIH HHS P01 HL116263NHLBI NIH HHS R01 HL173598NIDDK NIH HHS P30 DK058404NIDDK NIH HHS T32 DK101003
6 · The paper itself

Abstract

Aim: Extracellular communication via the transfer of vesicles and nanoparticles is now recognized to play an important role in tumor microenvironment interactions. Cancer cells upregulate and secrete abundant levels of Methods: To identify targets of Results: From an initial list of 96 potential mRNA targets, we identified and tested 15 targets, with 8 showing significant downregulation in the presence of Conclusion:

Indexed as

cingulincolorectal cancerinvasivenessmiR-100miR-125bmiRNAtight junctions

Identifiers

PMID39697634
PMCPMC11648436

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.