ArticleVeterinary medicine international2024
The Role of Ozonated Jerusalem Artichoke Ointment on the Healing of Surgically Created Full-Thickness Cutaneous Wounds in Rabbits.
Article in Veterinary medicine international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Phytochemical Composition and Mechanistic Pharmacology of Jerusalem Artichoke (Current issues in molecular biology · 2026Review
- The Role of a Biological Membrane in Healing Full-Thickness Cutaneous Wounds in Rats.Veterinary medicine international · 2026Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Jerusalem artichoke (J.A.) tubers contain compounds that exhibit anti-inflammatory effects and can minimize tissue damage. Ozone is an alternative antimicrobial and immunomodulatory agent for promoting tissue regeneration. The present study aimed to evaluate the therapeutic effect of the ozonated J.A. ointment on a surgically created full-thickness cutaneous wound in rabbit models. The previously prepared J.A. ointment was ozonated using a Herrmann generator, followed by a subsequent evaluation of its physical and antibacterial properties. Thirty healthy male albino rabbits were used in this study. The animals were divided into two equal groups: the control and treated group. An excisional wound model was used to assess wound healing activities. All of the animals underwent surgical preparation of their dorsal surfaces, and excisional lesions of 3 cm in diameter were created on each animal's dorsal surface of the thoracolumbar region. In the control group, the wounds were left untreated. The animals in the treatment group received a topical application of ozonated J.A. ointment twice daily for five days following the injury. The animals were euthanized on Days 7, 14, and 21 after the injury for histological evaluation. The agar well diffusion method demonstrated the antimicrobial efficacy of the ozonated J.A. ointment. Also, macroscopic and histopathological results showed a significant (
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