ReviewFrontiers in aging neuroscience2024
Magnetic resonance imaging of brain structural and functional changes in cognitive impairment associated with Parkinson's disease.
Review in Frontiers in aging neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- What's in a name? reframing advanced Parkinson's disease as a multidimensional state.Journal of neural transmission (Vienna, Austria : 1996) · 2026Review
- Neuroimaging evidence of microstructural alteration in Parkinson's disease with subjective cognitive decline.NPJ Parkinson's disease · 2026Article
- Deep learning approaches to map individual differences in macroscopic neural structure with variations in spatial navigation behavior.Neuropsychologia · 2026Article
- Data-driven subtyping of Parkinson's disease using MRI: current insights, challenges, and future directions.Frontiers in aging neuroscience · 2026Review
- The phase average wavelength of alpha rhythm in EEG signals of patients with Parkinson's disease combined with cognitive impairment.PloS one · 2026Article
- From Bench to Brain: Translating EV and Nanocarrier Research into Parkinson's Disease Therapies.Biology · 2025Review
- Resting-State EEG Alpha Asymmetry as a Potential Marker of Clinical Features in Parkinson's Disease.Journal of personalized medicine · 2025Article
- AI-assisted MRI segmentation analysis of brain region volume alterations in Parkinson's disease.Frontiers in human neuroscience · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cognitive impairment is a critical non-motor symptom of Parkinson's Disease (PD) that profoundly affects patients' quality of life. Magnetic Resonance Imaging (MRI) has emerged as a valuable tool for investigating the structural and functional brain changes associated with cognitive impairment in PD (PD-CI). MRI techniques enable the precise identification and monitoring of the onset and progression of cognitive deficits in PD. This review synthesizes recent literature on the use of MRI-based techniques, including voxel-based morphometry, diffusion tensor imaging, and functional MRI, in the study of PD-CI. By examining these imaging modalities, the article aims to elucidate the patterns of brain structural and functional alterations in PD-CI, offering critical insights that can inform clinical management and therapeutic strategies. In particular, this review provides a novel synthesis of recent advancements in understanding how specific MRI metrics, such as amplitude of low-frequency fluctuations, regional homogeneity, and functional connectivity, contribute to early detection and personalized treatment approaches for PD-CI. The integration of findings from these studies enhances our understanding of the neural mechanisms underlying cognitive impairment in PD and highlights the potential of MRI as a supportive tool in the clinical assessment and treatment of PD-CI.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.