Evidence map›Paper›PMID 39697435›Full record

ArticleFrontiers in neurology2024

The association between gait speed and falls in ambulatory adults with spinal muscular atrophy: a retrospective pilot study.

Kathryn Jira, Andrea Jaworek, Matti Allen, Songzhu Zhao, Kristina Kelly, W David Arnold, Bakri Elsheikh

Abstract read
In one paragraph

Article in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kathryn JiraDepartment of Neurology, The Ohio State University Wexner Medical Center, Columbus, OH, United States.
Andrea JaworekDepartment of Neurology, The Ohio State University Wexner Medical Center, Columbus, OH, United States.
Matti AllenDepartment of Neurology, The Ohio State University Wexner Medical Center, Columbus, OH, United States.
Songzhu ZhaoCenter for Biostatistics, The Ohio State University Wexner Medical Center, Columbus, OH, United States.
Kristina KellyNextGen Precision Health, University of Missouri, Columbia, MO, United States.
W David ArnoldNextGen Precision Health, University of Missouri, Columbia, MO, United States.
Bakri ElsheikhDepartment of Neurology, The Ohio State University Wexner Medical Center, Columbus, OH, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Fatigue and gait speed are established determinants of fall risk in patients with neurological disorders. However, data on adults with spinal muscular atrophy (SMA) is limited. The aim of this pilot study was to investigate falls and risk factors in adults with SMA. Methods: A retrospective chart review of ambulatory adults with genetically confirmed 5q-SMA included: age, sex, age of symptom onset, SMN2 copy number, BMI, and 6MWT distance and speed at minutes 1, 2, and 6. Results: Fourteen ambulatory patients were included in the analysis with an average follow-up of 36 months (range of 12-66 months). 10 patients were classified as fallers (F Discussion: These findings underscore the need for larger studies on fatigability and the importance of considering factors beyond gait speed alone.

Indexed as

6-Minute Walk Testambulationfallsfatigabilitygaitneuromuscularspinal muscular atrophy

Identifiers

PMID39697435
PMCPMC11652354

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.