Evidence map›Paper›PMID 39697104›Full record

ArticleEuropean psychiatry : the journal of the Association of European Psychiatrists2024

A prognostic model for predicting functional impairment in youth mental health services.

Frank Iorfino, Rafael Oliveira, Sally Cripps, Roman Marchant, Mathew Varidel, William Capon, Jacob J Crouse, Ante Prodan, Elizabeth M Scott, Jan Scott and 1 more

Abstract read
In one paragraph

Article in European psychiatry : the journal of the Association of European Psychiatrists, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. European Psychiatry: 2024 in review.European psychiatry : the journal of the Association of European Psychiatrists · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Frank IorfinoBrain and Mind Centre, The University of Sydney, Camperdown, NSWAustralia.ORCID 0000-0003-1109-0972
Rafael OliveiraBrain and Mind Centre, The University of Sydney, Camperdown, NSWAustralia.ORCID 0000-0002-3586-5026
Sally CrippsHuman Technology Institute, University of Technology Sydney, Sydney, NSWAustralia.ORCID 0000-0003-3207-172X
Roman MarchantHuman Technology Institute, University of Technology Sydney, Sydney, NSWAustralia.ORCID 0000-0002-0969-2352
Mathew VaridelBrain and Mind Centre, The University of Sydney, Camperdown, NSWAustralia.ORCID 0000-0002-1648-8317
William CaponBrain and Mind Centre, The University of Sydney, Camperdown, NSWAustralia.ORCID 0000-0001-6500-9629
Jacob J CrouseBrain and Mind Centre, The University of Sydney, Camperdown, NSWAustralia.ORCID 0000-0002-3805-2936
Ante ProdanBrain and Mind Centre, The University of Sydney, Camperdown, NSWAustralia.ORCID 0000-0001-9684-7967
Elizabeth M ScottBrain and Mind Centre, The University of Sydney, Camperdown, NSWAustralia.ORCID 0000-0003-3907-0324
Jan ScottAcademic Psychiatry, Institute of Neuroscience, Newcastle University, Newcastle, UK.ORCID 0000-0002-7203-8601
Ian B HickieBrain and Mind Centre, The University of Sydney, Camperdown, NSWAustralia.

Funding

Australian Government Research Training ProgramBill and Patricia Richie FoundationMedical Research Future Fund Applied Artificial Intelligence Research in Health GrantNHMRC EL1 Investigator GrantThe Johnston Fellowship
6 · The paper itself

Abstract

backgroundFunctional impairment is a major concern among those presenting to youth mental health services and can have a profound impact on long-term outcomes. Early recognition and prevention for those at risk of functional impairment is essential to guide effective youth mental health care. Yet, identifying those at risk is challenging and impacts the appropriate allocation of indicated prevention and early intervention strategies.

methodsWe developed a prognostic model to predict a young person's social and occupational functional impairment trajectory over 3 months. The sample included 718 young people (12-25 years) engaged in youth mental health care. A Bayesian random effects model was designed using demographic and clinical factors and model performance was evaluated on held-out test data via 5-fold cross-validation.

resultsEight factors were identified as the optimal set for prediction: employment, education, or training status; self-harm; psychotic-like experiences; physical health comorbidity; childhood-onset syndrome; illness type; clinical stage; and circadian disturbances. The model had an acceptable area under the curve (AUC) of 0.70 (95% CI, 0.56-0.81) overall, indicating its utility for predicting functional impairment over 3 months. For those with good baseline functioning, it showed excellent performance (AUC = 0.80, 0.67-0.79) for identifying individuals at risk of deterioration.

conclusionsWe developed and validated a prognostic model for youth mental health services to predict functional impairment trajectories over a 3-month period. This model serves as a foundation for further tool development and demonstrates its potential to guide indicated prevention and early intervention for enhancing functional outcomes or preventing functional decline.

Indexed as

Mental Health ServicesAdolescentAdolescent Health ServicesAdultBayes TheoremChildFemaleHumansMaleMental DisordersPrognosisYoung Adultearly interventionfunctional impairmentprecision psychiatrypredictionprognostic toolsyouth mental health

Identifiers

PMID39697104
PMCPMC11733617

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.