Evidence map›Paper›PMID 39696755›Full record

Trial reportJournal of neurosurgical anesthesiology2025

Feasibility of Alerting Systems and Family Care Partner Support for Postoperative Delirium Prevention.

Phillip E Vlisides, Nathan Runstadler, Selena Martinez, Jacqueline W Ragheb, Graciela Mentz, Aleda Leis, Amanda Schoettinger, Kimberly Hickey, Amy McKinney, Joseph Brooks and 6 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of neurosurgical anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Phillip E VlisidesDepartment of Anesthesiology, Michigan Medicine, Ann Arbor, MI.
Nathan RunstadlerDepartment of Anesthesiology, Michigan Medicine, Ann Arbor, MI.
Selena MartinezDepartment of Anesthesiology, Michigan Medicine, Ann Arbor, MI.
Jacqueline W RaghebDepartment of Anesthesiology, University of Miami Miller School of Medicine, Miami, FL.
Graciela MentzDepartment of Anesthesiology, Michigan Medicine, Ann Arbor, MI.
Aleda LeisDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI.
Amanda SchoettingerDepartment of Social Work, University of Michigan.
Kimberly HickeyDepartment of Nursing, Michigan Medicine, Ann Arbor, MI.
Amy McKinneyDepartment of Anesthesiology, Michigan Medicine, Ann Arbor, MI.
Joseph BrooksDepartment of Orthopaedic Surgery, Michigan Medicine, Ann Arbor, MI.
Mackenzie ZierauCollege of Health Professions, University of Detroit Mercy, Detroit, MI.
Alexandra NorcottDepartment of Internal Medicine, Division of Geriatric and Palliative Medicine, Michigan Medicine, Ann Arbor, MI.
Lona ModyDepartment of Internal Medicine, Division of Geriatric and Palliative Medicine, Michigan Medicine, Ann Arbor, MI.
Sharon K InouyeAging Brain Center, Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA.
Michael S AvidanDepartment of Anesthesiology, Washington University School of Medicine, St. Louis, MO.
Lillian MinDepartment of Internal Medicine, Division of Geriatric and Palliative Medicine, Michigan Medicine, Ann Arbor, MI.

Funding

Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
Research Education CoreP30AG024824 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Lona Mody, RAYMOND L YUNG · 2004 to 2026
$29.2M
Preventing Infections and Antimicrobial Resistance in the Aging Population: Translational Research and Training ProgramK24AG050685 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Lona Mody · 2015 to 2026
$1.4M
NCATS NIH HHS UL1 TR002240NIA NIH HHS K24 AG050685NIA NIH HHS P30 AG024824University of Michigan Claude D. Pepper Center P30AG024824
6 · The paper itself

Abstract

backgroundThe objective of this study was to determine whether postoperative pager alerts to the Hospital Elder Life Program (HELP), a delirium prevention service, would accelerate program enrollment for older surgical patients. This study also tested feasibility of family care partner interventions for delirium prevention.

methodsThis single-center, pilot clinical trial factorially randomized 57 non-cardiac surgical patients ≥70 years of age to 4 arms: (1) standard care, (2) pager alerts to accelerate HELP enrollment, (3) family care partner-based delirium prevention interventions, or (4) a combined arm with both HELP and family interventions. The primary clinical outcome was delirium (assessed through the Confusion Assessment Method).

resultsIn the pager alerting arms, 13/24 (54%) participants were enrolled by HELP on postoperative day 1 compared with 0/26 (0%, P <0.001) in the non-alerting arms. Median [interquartile range] time spent in delirium prevention protocols was significantly longer in pager alerting arms than in non-alerting arms (39 [5 to 75] min vs. 0 [0 to 0] min; P <0.001). Family care partners spent 18 [11 to 25)] hours at the bedside over the first 3 postoperative days. There was no significant difference in delirium occurrence in participants randomized to pager alert arms compared with non-alerting arms (odds ratio, 1.02, 95% CI, 0.97-1.07; P =0.390). Similarly, there was no significant difference in delirium occurrence in family intervention arms compared with nonintervention arms (odds ratio, 0.97; 95% CI 0.93-10.02; P =0.270).

conclusionsPager alerts significantly reduced time to HELP enrollment, albeit without reducing delirium incidence in this pilot study. Family care partners spent substantial time at the bedside during the study period.

Indexed as

CaregiversDeliriumPostoperative ComplicationsAgedAged, 80 and overFamilyFeasibility StudiesFemaleHumansMalePilot Projectsclinical decision support systemsclinical trialdeliriumfeasibility studieshealth services for the aged

Identifiers

PMID39696755
PMCPMC12177099

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.