Evidence map›Paper›PMID 39696750›Full record

ArticleObesity (Silver Spring, Md.)2025

Contemporary treatment patterns of overweight and obesity: insights from the Mass General Brigham health care system.

John W Ostrominski, Kavishwar B Wagholikar, Kelly Olsson, Ozan Unlu, David Zelle, Sanjay Kumar, Austen M Smith, Joshua C Toliver, Wojciech Michalak, Anthony Fabricatore and 8 more

Abstract readMulticenter Study
In one paragraph

Article in Obesity (Silver Spring, Md.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

John W OstrominskiDivision of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-2866-9414
Kavishwar B WagholikarHarvard Medical School, Boston, Massachusetts, USA.
Kelly OlssonNovo Nordisk Inc., Plainsboro, New Jersey, USA.
Ozan UnluDivision of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
David ZelleDivision of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Sanjay KumarHarvard Medical School, Boston, Massachusetts, USA.
Austen M SmithDivision of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Joshua C ToliverNovo Nordisk Inc., Plainsboro, New Jersey, USA.
Wojciech MichalakNovo Nordisk Inc., Plainsboro, New Jersey, USA.
Anthony FabricatoreNovo Nordisk Inc., Plainsboro, New Jersey, USA.
Bríain Ó HartaighNovo Nordisk Inc., Plainsboro, New Jersey, USA.
Heather J BaerHarvard Medical School, Boston, Massachusetts, USA.
Christopher P CannonDivision of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Caroline M ApovianDivision of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-8029-1922
Naomi D L FisherDivision of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Jorge PlutzkyDivision of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Benjamin M SciricaDivision of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Alexander J BloodDivision of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-8391-2536

Funding

Novo Nordisk Inc.Novo Nordisk, Inc.
6 · The paper itself

Abstract

objectiveThe objective of this study was to describe the prevalence of obesity, obesity-related conditions (ORCs), and antiobesity medication (AOM) eligibility and prescribing practice among eligible patients in a large health care system.

methodsIn this cross-sectional analysis of the multicenter Mass General Brigham health care system (Boston, Massachusetts) spanning 2018 to 2022, adults eligible for AOMs (BMI ≥ 30 kg/m

resultsOf 2,469,474 adults (mean [SD], age 53 [19] years; 57% female; BMI 28.1 [6.3] kg/m

conclusionsAlthough nearly one-half of all patients in a large health care system were AOM-eligible by guidelines and regulatory labeling, only 1% of those who were eligible were prescribed AOMs.

Indexed as

Anti-Obesity AgentsObesityOverweightPractice Patterns, Physicians'AdultAgedBody Mass IndexCross-Sectional StudiesFemaleHumansMaleMassachusettsMiddle AgedPrevalenceAnti-Obesity Agents

Identifiers

PMID39696750
PMCPMC11774016

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.