Evidence map›Paper›PMID 39696653›Full record

ArticleBiotechnology for biofuels and bioproducts2024

Antimicrobial peptide production with Corynebacterium glutamicum on lignocellulosic side streams.

Daniel Waldschitz, Mark-Richard Neudert, Jakob Kitzmüller, Jae Hwi Bong, Yannick Bus, Eva Maria Karner, Peter Sinner, Oliver Spadiut

Abstract read
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In one paragraph

Article in Biotechnology for biofuels and bioproducts, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Daniel WaldschitzResearch Group Bioprocess Technology, Institute of Chemical, Environmental and Bioscience Engineering, TU Wien, Gumpendorferstraße 1A, Vienna, A-1060, Austria.
Mark-Richard NeudertResearch Group Bioprocess Technology, Institute of Chemical, Environmental and Bioscience Engineering, TU Wien, Gumpendorferstraße 1A, Vienna, A-1060, Austria.
Jakob KitzmüllerResearch Group Bioprocess Technology, Institute of Chemical, Environmental and Bioscience Engineering, TU Wien, Gumpendorferstraße 1A, Vienna, A-1060, Austria.
Jae Hwi BongResearch Group Bioprocess Technology, Institute of Chemical, Environmental and Bioscience Engineering, TU Wien, Gumpendorferstraße 1A, Vienna, A-1060, Austria.
Yannick BusResearch Group Bioprocess Technology, Institute of Chemical, Environmental and Bioscience Engineering, TU Wien, Gumpendorferstraße 1A, Vienna, A-1060, Austria.
Eva Maria KarnerResearch Group Bioprocess Technology, Institute of Chemical, Environmental and Bioscience Engineering, TU Wien, Gumpendorferstraße 1A, Vienna, A-1060, Austria.
Peter SinnerResearch Group Bioprocess Technology, Institute of Chemical, Environmental and Bioscience Engineering, TU Wien, Gumpendorferstraße 1A, Vienna, A-1060, Austria.
Oliver SpadiutResearch Group Bioprocess Technology, Institute of Chemical, Environmental and Bioscience Engineering, TU Wien, Gumpendorferstraße 1A, Vienna, A-1060, Austria. oliver.spadiut@tuwien.ac.at.

Funding

Bio-Based Industries Joint Undertaking No 790507 (iFermenter)
6 · The paper itself

Abstract

backgroundBiorefineries usually focus on the production of low-value commodities, such as bioethanol, platform chemicals or single cell protein. Shifting production to bioactive compounds, such as antimicrobial peptides, could provide an opportunity to increase the economic viability of biorefineries.

resultsRecombinant production of the antimicrobial peptide pediocin PA-1 in Corynebacterium glutamicum was transferred from yeast extract-based media to minimal media based on lignocellulosic spent sulfite liquor. Induced batch, fed batch, and extended batch process modes were compared for highest pediocin PA-1 production.

conclusionFor pediocin PA-1 production on lignocellulosic residues, extended batch cultivation was identified as the optimal process mode, producing up to

Indexed as

Antimicrobial peptideCorynebacterium glutamicumLignocellulosic feedstockPediocin PA-1Recombinant productionSpent sulfite liquor

Identifiers

PMID39696653
PMCPMC11657226

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.