Evidence map›Paper›PMID 39696563›Full record

ArticleMolecular cancer2024

Incidence, risk factors, and epidemiological trends of tracheal cancer: a global analysis.

Junjie Huang, Mingtao Chen, Lin Zhang, Xu Lin, Don Eliseo Lucero-Prisno, Claire Chenwen Zhong, Wanghong Xu, Zhi-Jie Zheng, Mellissa Withers, Martin C S Wong and 2 more

Abstract read
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In one paragraph

Article in Molecular cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Junjie HuangThe Jockey Club School of Public Health and Primary Care, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong SAR, China.
Mingtao ChenThe Jockey Club School of Public Health and Primary Care, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong SAR, China.
Lin ZhangThe School of Public Health and Preventive Medicine, Monash University, Victoria, Australia.
Xu LinDepartment of Thoracic Surgery, School of Medicine, The First Affiliated Hospital, Zhejiang University, Hangzhou, Zhejiang, China.
Don Eliseo Lucero-PrisnoDepartment of Global Health and Development, London School of Hygiene and Tropical Medicine, London, UK.
Claire Chenwen ZhongThe Jockey Club School of Public Health and Primary Care, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong SAR, China. chenwenzhong@cuhk.edu.hk.
Wanghong XuSchool of Public Health, Fudan University, Shanghai, China.
Zhi-Jie ZhengDepartment of Global Health, School of Public Health, Peking University, Beijing, China.
Mellissa WithersDepartment of Population and Health Sciences, Institute for Global Health, University of Southern California, Los Angeles, USA. mwithers@usc.edu.
Martin C S WongThe Jockey Club School of Public Health and Primary Care, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong SAR, China. wong_martin@cuhk.edu.hk.
N. C. D. Global Health Working Group
Association of Pacific Rim Universities (APRU)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTracheal cancer is a rare malignancy with limited research but high mortality rates. This study aims to analyse recent data to understand the global burden, trends, and risk factors for tracheal cancer, facilitating improved prevention and treatment strategies.

methodsWe conducted a study on tracheal cancer using data from the Global Cancer Observatory and the Cancer Incidence in Five Continents databases. We collected information on the incidence of tracheal cancer, risk factors, and the Human Development Index (HDI) at the country level. The univariate linear regression was used to explore the relationship between tracheal cancer and the various risk factors. We utilised joinpoint regression analysis to calculate the Average Annual Percentage Change (AAPC) in tracheal cancer incidence.

resultsThe global age-standardised rate of incidence of tracheal cancer was 2.9 per 10 million (3,472 cases in total) in 2022, with the highest regional incidence observed in Central and Eastern Europe (ASR = 9.0) and the highest national incidence in Hungary (12.5). Higher incidence was found among the males (3.8) than females (2.0); among the older adults aged 50-74 (11.9) than the younger population aged 15-49 (1.2). A higher tracheal cancer incidence ratio was associated with higher levels of smoking, alcohol drinking, diabetes, lipid disorders, and HDI. Despite the overall decreasing trends for all population groups (highest decrease in Thailand; AAPC: -15.06, 95% CI: -21.76 to -7.78, p = 0.002), there was an increase in some female populations (highest increase in Colombia, AAPC: 19.28, 95% CI: 16.48 to 22.15, p < 0.001) and younger populations (highest increase in Ireland; AAPC: 29.84, 95% CI: 25.74 to 34.06, p < 0.001).

conclusionThis study provides a comprehensive analysis of tracheal cancer, focusing on risk factors and population-level trends. There has been an overall decreasing trend in the incidence of tracheal cancer, particularly among males and older adults, while the decline is less pronounced in females and younger individuals. Further research is needed to explore the underlying drivers of these epidemiological trends.

Indexed as

Global HealthTracheal NeoplasmsAdolescentAdultAgedFemaleHumansIncidenceMaleMiddle AgedRisk FactorsYoung AdultCancer registryEpidemiologyRisk factorTracheal cancer

Identifiers

PMID39696563
PMCPMC11654256

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.