ReviewJournal of orthopaedic surgery and research2024
Advances in perioperative pain management for total knee arthroplasty: a review of multimodal analgesic approaches.
Review in Journal of orthopaedic surgery and research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
57 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Risk prediction models for blood transfusion in patients undergoing total hip and knee arthroplasty: a systematic review and meta-analysis.Annals of medicine · 2026Pooled it
- Duloxetine for postoperative pain management in total hip and knee arthroplasty: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2026Pooled it
- The safety and efficacy of peri-operative nefopam for analgesia in hip and knee arthroplasty: A systematic review and meta-analysis.European journal of clinical pharmacology · 2026Pooled it
- Genicular Nerve Radiofrequency Ablation for Persistent Postsurgical Pain After Total Knee Arthroplasty: A Systematic Review of Clinical Effectiveness and Safety.BioMed research international · 2026Pooled it
- Peripheral nerve blocks for total knee arthroplasty: a bibliometric and visual analysis, 2016-2025.Frontiers in medicine · 2026Pooled it
- Changes in knee outcome measures following later-stage exercise interventions implemented ≤ 12 weeks vs. > 12 weeks after total knee arthroplasty: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2025Pooled it
- The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2025Pooled it
- Pharmacologic pain management strategies for reducing postoperative pain in total knee arthroplasty: a systematic review from molecular mechanisms to clinical efficiency.Archives of orthopaedic and trauma surgery · 2025Pooled it
- Liposomal bupivacaine versus conventional anesthetics in adductor canal block for total knee arthroplasty: a meta-analysis of randomized controlled trials.BMC anesthesiology · 2025Pooled it
- Analgesic efficacy of liposomal bupivacaine adductor canal block combined with periarticular infiltration after total knee arthroplasty: a prospective, double-blind, randomized controlled trial.BMC anesthesiology · 2026Trial
- No short term pain benefit of adding corticosteroids to periarticular analgesia after total knee arthroplasty: a prospective, double-blind, randomized controlled trial.Journal of orthopaedic surgery and research · 2026Trial
- [Observation on analgesic efficacy of ultrasound-guided high fascia iliac compartment block for tourniquet-related pain following total knee arthroplasty].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025Trial
- Perioperative blood loss of sequential administration of hemocoagulase Agkistrodon and Tranexamic acid for primary total knee arthroplasty: a randomized controlled trial.Journal of orthopaedic surgery and research · 2025Trial
- The efficacy of liposomal bupivacaine in parasacral ischial plane block for pain management after total knee arthroplasty: a randomized controlled trial.Journal of orthopaedic surgery and research · 2025Trial
- EMMATKA trial: the effects of mobilization with movement following total knee arthroplasty in women: a single-blind randomized controlled trial.Journal of orthopaedic surgery and research · 2025Trial
- Comparing different timings of tourniquet application in total knee arthroplasty: effects on postoperative pain and bone cement interface.Journal of orthopaedic surgery and research · 2025Trial
- Efficacy and Safety Comparison of Ulinastatin Versus Flurbiprofen Axetil for Preemptive Analgesia in Reducing Opioid Burden After Total Knee Arthroplasty: A Randomized Controlled Trial.Journal of pain research · 2025Trial
- Comparative Study of Effect of Periarticular Fentanyl and Dexmedetomidine Injection for Pain Management in Total Knee Arthroplasty a Randomized Control Trial.Journal of orthopaedic case reports · 2026Article
- Efficacy of popliteal plexus block for opioid sparing and pain management after lower extremity surgery: a meta-analysis.The Korean journal of pain · 2026Article
- The Effect of the Coronal Alignment of Extension Stem on Component Displacement and Stress During Total Knee Arthroplasty: A Finite Element Study.Orthopaedic surgery · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite significant advancements in total knee arthroplasty (TKA), managing postoperative pain remains a substantial clinical challenge. With advances in surgical techniques and pharmacology, TKA perioperative analgesic strategies continue to evolve, necessitating ongoing reassessment of current data. Multimodal analgesia has become the standard for perioperative pain management in TKA; however, variations in its specific components and applications across studies create challenges in selecting the optimal analgesic approach. Evaluating these pain management strategies is essential for understanding their benefits, limitations, and appropriate use, allowing the development of individualized perioperative analgesic plans. This review aims to summarize current research on perioperative pain control in TKA and assess the effectiveness of different analgesic interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.