Evidence map›Paper›PMID 39696498›Full record

ArticleJournal of nanobiotechnology2024

Single-cell RNA sequencing uncovers heterogenous immune cell responses upon exposure to food additive (E171) titanium dioxide.

Haribalan Perumalsamy, Xiao Xiao, Hyoung-Yun Han, Jung-Hwa Oh, Seokjoo Yoon, Min Beom Heo, Tae Geol Lee, Hyun-Yi Kim, Tae-Hyun Yoon

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nanobiotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Chiral Titanium Dioxide Nanoparticles Induce Breast Cancer Lung Metastasis.Advanced materials (Deerfield Beach, Fla.) · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Haribalan PerumalsamyInstitute for Next Generation Material Design, Hanyang University, Seoul, 04763, Republic of Korea.
Xiao XiaoDepartment of Chemistry, College of Natural Sciences, Hanyang University, Seoul, 04763, Republic of Korea.
Hyoung-Yun HanDepartment of Predictive Toxicology, Korea Institute of Toxicology, Daejeon, Republic of Korea.
Jung-Hwa OhDepartment of Predictive Toxicology, Korea Institute of Toxicology, Daejeon, Republic of Korea.
Seokjoo YoonDepartment of Predictive Toxicology, Korea Institute of Toxicology, Daejeon, Republic of Korea.
Min Beom HeoNanosafety Metrology Center, Korea Research Institute of Standards and Science (KRISS), Daejeon, Republic of Korea.
Tae Geol LeeNanosafety Metrology Center, Korea Research Institute of Standards and Science (KRISS), Daejeon, Republic of Korea.
Hyun-Yi KimInstitute for Next Generation Material Design, Hanyang University, Seoul, 04763, Republic of Korea.
Tae-Hyun YoonInstitute for Next Generation Material Design, Hanyang University, Seoul, 04763, Republic of Korea. taeyoon@hanyang.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prospective use of food additive titanium dioxide (E171 TiO

Indexed as

Food AdditivesKiller Cells, NaturalRats, Sprague-DawleySingle-Cell AnalysisTitaniumAnimalsCytokinesImmunity, InnateMaleRatsSequence Analysis, RNATranscriptomeCytokinesFood AdditivesTitaniumtitanium dioxideE171 TiO2HeterogeneityImmune responseRat peripheral blood mononuclear cellsscRNAseq analysis

Identifiers

PMID39696498
PMCPMC11657454

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.