Evidence map›Paper›PMID 39696346›Full record

ReviewCancer cell international2024

Exosomes and breast cancer angiogenesis; Highlights in intercellular communication.

Parisa Khanicheragh, Zahra Abbasi-Malati, Solmaz Saghebasl, Parisa Hassanpour, Soheil Zamen Milani, Reza Rahbarghazi, Akbar Hasani

Abstract readReview
In one paragraph

Review in Cancer cell international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Parisa KhanicheraghDrug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Zahra Abbasi-MalatiStudent Committee Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Solmaz SaghebaslStem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Parisa HassanpourDepartment of Clinical Biochemistry and Laboratory Medicine, Tabriz University of Medical Sciences, Tabriz, 5165687386, Iran.
Soheil Zamen MilaniStudent Committee Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Reza RahbarghaziDepartment of Applied Cell Sciences, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran. rahbarghazir@tbzmed.ac.ir.
Akbar HasaniDrug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. dr.akbarhasani@gmail.com.

Funding

Tabriz University of Medical Sciences 71007
6 · The paper itself

Abstract

Breast cancer (BC) is a prevalent and highly lethal cancer in females. Like other cancer types, the intricate cellular and molecular heterogeneity leads to the variation of therapeutic outcomes. The development and progression of blood vessels increase the tumor cell expansion and metastasis to remote sites. Based on several pieces of scientific data, different mediators and cells are involved in the promotion of angiogenesis into the tumor parenchyma. Recent data have indicated the critical role of extracellular vesicles, especially exosomes (Exos), in the transfer of angiogenesis molecules between the BC cells. Due to unique physicochemical properties, and the transfer of certain signaling molecules, Exos are at the center of attention in terms of biomarkers and therapeutic bullets in cancer patients. Along with these statements, understanding the modulatory role of Exos in BC angiogenesis seems critical in the clinical setting. Here, the mechanisms by which BC cells can orchestrate the angiogenesis phenomenon via Exos are discussed in detail. The present study can help us to understand the pro-/anti-angiogenesis role of Exos in BC and to design better oncostatic strategies.

Indexed as

AngiogenesisBreast cancerExosomesExtracellular vesiclesParacrine communication

Identifiers

PMID39696346
PMCPMC11656829

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.