Evidence map›Paper›PMID 39696293›Full record

ArticleBMC oral health2024

In vitro comparison of Enterococcus Faecalis survival in dentinal tubules following root canal therapy with AH plus, endoseal MTA, and cold ceramic sealers.

Fatemeh Mokhtari, Jalil Modaresi, Ali Hasanzade Salmasi, Nima Khamisi, Hengameh Zandi, Katayoun Lesani

Abstract readComparative Study
In one paragraph

Article in BMC oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Membrane Vesicles ofMicroorganisms · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fatemeh MokhtariDepartment of Endodontics, Dental School, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Jalil ModaresiDepartment of Endodontics, Dental School, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Ali Hasanzade SalmasiDepartment of Endodontics, Dental School, AJA University of Medical Sciences, Tehran, Iran. endohasanzade@gmail.com.
Nima KhamisiSchool of Dentistry, Islamic Azad University (Khorasgan Branch), Isfahan, Iran.
Hengameh ZandiDepartment of Microbiology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Katayoun LesaniDepartment of Oral and Maxillofacial Radiology, School of Dentistry, Iran University of Medical Sciences, Azadi St., Jamalzadeh St., Jamshid Alley, Tehran, 1313883851, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEnterococcus faecalis (E. faecalis) is the most common microorganism responsible for post-endodontic infections, which can penetrate deep into dentinal tubules. This study aimed to compare the survival of E. faecalis in dentinal tubules following root canal therapy with AH Plus (AHP), Endoseal MTA (ESM), and cold ceramic (CC) sealers.

methodsIn this in vitro experimental study, 80 single-canal human teeth were decoronated at the cementoenamel junction. The root canals were cleaned and shaped, and auto-clave sterilized after smear layer removal. The roots were then inoculated with E. faecalis, and incubated for 3 weeks. The teeth were randomly assigned to four groups (n = 20) for root canal obturation with AHP, ESM, and CC sealers and 2% gutta-percha with the cold lateral compaction technique. The fourth group served as the control group. After 30 days, dentin chips were collected from the canals, and cultured on blood agar. The colony count was reported and analyzed by the Kruskal-Wallis test (alpha = 0.05).

resultsThe mean colony count was 23.73 ± 13.84 in the AHP, 34.78 ± 18.75 in the ESM, and 28.47 ± 13.73 in the CC group after 30 days. The difference in this regard was not significant among the three experimental groups (P = 0.102).

conclusionsWithin the limitations of this in vitro study, the results indicated comparable antibacterial activity of AHP, ESM, and CC sealers against E. faecalis in infected dentinal tubules after 30 days.

Indexed as

Aluminum CompoundsCalcium CompoundsDentinDrug CombinationsEnterococcus faecalisEpoxy ResinsOxidesRoot Canal Filling MaterialsSilicatesBacterial LoadCeramicsColony Count, MicrobialDental Pulp CavityGutta-PerchaHumansIn Vitro TechniquesAluminum CompoundsCalcium CompoundsDrug Combinationsepoxy resin-based root canal sealerEpoxy ResinsGutta-Perchamineral trioxide aggregateOxidesRoot Canal Filling MaterialsSilicatesAnti-bacterial agentsEnterococcus faecalisEpoxy Resin-based root canal sealerRoot canal therapy

Identifiers

PMID39696293
PMCPMC11658299

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.