ArticleBMC gastroenterology2024
Association between ZJU index and gallstones in US adult: a cross-sectional study of NHANES 2017-2020.
Article in BMC gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed.
- Association between GLM7 glycolipid metabolism index and female infertility: A cross-sectional analysis of NHANES 2013-2020.Medicine · 2026Article
- ZJU index and prevalence of kidney stones in US adults: evidence for a threshold association from NHANES 2007-2018.Translational andrology and urology · 2026Article
- The association between ZJU index and kidney stone risk: a machine learning approach on NHANES 2007-2018.BMC urology · 2026Article
- Association between the Zhejiang University index and metabolic dysfunction-associated fatty liver disease as analyzed in National Health and Nutrition Examination Survey: A retrospective observational study.The Journal of international medical research · 2026Observational
- Association between ZJU index and glycemic outcomes in individuals with impaired fasting glucose: a retrospective multicenter Chinese cohort study.Frontiers in endocrinology · 2026Article
- Association between the Zhejiang University index and kidney stone risks in US adults: evidence from NHANES 2007-2018.American journal of clinical and experimental urology · 2026Article
- Exploring the association between the ZJU index and overactive bladder: a cross-sectional study based on NHANES 2011-2018.Translational andrology and urology · 2025Article
- Association between Zhejiang University index and metabolic dysfunction-associated steatotic liver disease in patients with type 2 diabetes mellitus.World journal of diabetes · 2025Article
- The mediating effect of serum total testosterone in the association between the ZJU index and PCOS.Scientific reports · 2025Article
- Association between a diabetes-predictive index and diabetes-related kidney disease in U.S. adults: A cross-sectional study.Preventive medicine reports · 2025Article
- Red blood cell distribution width to albumin ratio as a predictor of gallstones in US adults: a NHANES-based cross-sectional study.Journal of health, population, and nutrition · 2025Article
- Novel Insights into the Association of ZJU index with Periodontitis in US participants: a cross-sectional study.Lipids in health and disease · 2025Article
- Formation of non-cholesterol gallstones in populations within clonorchiasis endemic regions is closely related to Clonorchis sinensis infection.BMC gastroenterology · 2025Article
- Relationship Between the ZJU Index and Infertility Risk in Reproductive-Aged US Women: An Analysis of NHANES 2013-2018.International journal of women's health · 2025Article
- Association between the ZJU index and gallstone prevalence in a Chinese adult population: a cross-sectional study.Frontiers in medicine · 2025Article
- The association between the ZJU index and chronic kidney disease: Evidence from the NHANES and GEO databases.Digital healthArticle
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Abstract
backgroundBased on triglyceride, body mass index (BMI), alanine aminotransferase/ aspartate aminotransferase ratio, fasting blood glucose, the ZJU index is proven to be a novel and effective parameter for screening NAFLD in Chinese. This study aims to evaluate the correlation between ZJU values and the risk of developing gallstones.
methodsThe data from the National Health and Nutrition Examination Survey (NHANES) database during the period from 2017 to 2020 were analyzed in this cross-sectional study. And 6155 participants were included to assess the correlation between the ZJU index and the formation of gallstones through multivariate logistic regression, receiver operating characteristic (ROC) curve, subgroup analysis, and restricted cubic spline regression (RCS) analyses.
resultsIn this population-based study, 6155 participants aged 18 years and older were included, among which, 671 had gallstones. Logistic regression and RCS regression analyses indicated a significant positive non-linearly correlation between the ZJU index and the prevalence of gallstones (OR = 1.044, 95% CI: 1.032, 1.056), with an inflection point of 40.6. Subgroup analysis further revealed a stronger correlation between the risk of developing gallstones and the ZJU index in females. ROC analysis indicated that the ZJU index (AUC = 0.653) can serve as a more robust predictor for developing gallstones compared to traditional indices, with a sensitivity of 55.9%, a specificity of 67.1% and a cutoff of 43.4.
conclusionThis study provides evidence that elevated the ZJU index is correlated with an increased risk of developing gallstones.
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