Evidence map›Paper›PMID 39695957›Full record

Trial reportBMC anesthesiology2024

Effect of continuous infusion in alleviating pain during male urethral catheterization.

Lijun Cao, Xin Qi, Dan Liu, Xincheng Mao, Liu Luo, Mengjiang Liu, Xinyi Wen, Chunhong Cui, Jia Qi, Junmei Xu and 1 more

Abstract readRandomized Controlled TrialMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC anesthesiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lijun Cao *Department of Anesthesiology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Xin Qi *Department of Ophthalmology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Dan LiuDepartment of Anesthesiology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Xincheng MaoDepartment of Anesthesiology, Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University, Zhuzhou, Hunan, 412000, China.
Liu LuoDepartment of Anesthesiology, Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University, Zhuzhou, Hunan, 412000, China.
Mengjiang LiuDepartment of Anesthesiology, The First People's Hospital of Chenzhou, Chenzhou, Hunan, 423000, China.
Xinyi WenDepartment of Anesthesiology, Wenzhou People's Hospital, Wenzhou, Zhejiang, 325000, China.
Chunhong CuiDepartment of Otolaryngology, the Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, 550001, China.
Jia QiDepartment of Anesthesiology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Junmei XuDepartment of Anesthesiology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Yulong CuiDepartment of Anesthesiology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China. cuiyulong@csu.edu.cn.

Funding

National Key Research and Development Program of China 2018YFC2001902National Nature Science Foundation of China 82301264Outstanding Youth Fund Program, Natural Science Foundation of Hunan Province 2023JJ20085The Science and Technology Innovation Program of Hunan Province 2023RC3084
6 · The paper itself

Abstract

aimsThe aim of this study was to explore whether continuous infusion causing lubrication can effectively alleviate pain during male urethral catheterization.

methodsThis prospective, multicenter, double-blinded study included 190 male patients scheduled for urethral catheterization. Patients were randomly allocated into four groups: Group A: the catheter was lubricated with paraffin; Group B: the catheter was lubricated with compound lidocaine gel; Group C: the pump continuously infusing with sterilized water; Group D: the pump continuously infusing with 2% lidocaine. The primary outcome was the visual analogue scale (VAS) scores. Statistical analysis system (SAS) (version 9.4) was used to perform all the statistical analyses. Significance for all results was set at P < 0.05.

resultsThe VAS of Group D was the lowest (18.90 ± 11.44), followed by the Group C (33.00 ± 11.07), and the VAS of Group A was the highest (53.98 ± 14.76). There were significant differences in VAS in Group D compared to Group A(P < 0.0001), Group B(P < 0.0001) and Group C (P < 0.0001), Group C compared to Group A (P < 0.0001) and Group B(P < 0.0001), Group B compared to Group A (P < 0.0001), indicating that patients treated with lidocaine infusion (Group D) experienced significantly less pain than did those in the other three groups.

conclusionsContinuous infusion with sterilized water during catheterization is an efficient method for lubricating the urethral mucosa; furthermore, infusion with 2% lidocaine provides better analgesia as well as lubrication.

trial registrationThe study protocol was registered in the Chinese Clinical Trial Registry (ChiCTR2300070866) ( https://www.chictr.org.cn/showproj.html?proj=194591 ) on Apr. 25th, 2023.

Indexed as

Anesthetics, LocalLidocaineUrinary CatheterizationAdultAgedDouble-Blind MethodHumansMaleMiddle AgedPainPain MeasurementProspective StudiesAnesthetics, LocalLidocaineContinuous infusionMulticenter studyPainUrethral catheterization

Identifiers

PMID39695957
PMCPMC11657273

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.