ArticleBMC bioinformatics2024
Informeasure: an R/bioconductor package for quantifying nonlinear dependence between variables in biological networks from an information theory perspective.
Article in BMC bioinformatics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Investigate synergistic and competitive regulation between miRNAs by using a multivariate information measurement.BMC bioinformatics · 2026Article
- Utilizing partial information decomposition to evaluate the complex interplay between microRNA and RNA-binding protein in regulating the shared target mRNA.Scientific reports · 2025Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
backgroundUsing information measures to infer biological regulatory networks can capture nonlinear relationships between variables. However, it is computationally challenging, and there is a lack of convenient tools.
resultsWe introduce Informeasure, an R package designed to quantify nonlinear dependencies in biological regulatory networks from an information theory perspective. This package compiles a comprehensive set of information measurements, including mutual information, conditional mutual information, interaction information, partial information decomposition, and part mutual information. Mutual information is used for bivariate network inference, while the other four estimators are dedicated to trivariate network analysis.
conclusionsInformeasure is a turnkey solution, allowing users to utilize these information measures immediately upon installation. Informeasure is available as an R/Bioconductor package at https://bioconductor.org/packages/Informeasure .
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.