Evidence map›Paper›PMID 39695820›Full record

ReviewBiotechnology for biofuels and bioproducts2024

Reduction of nicotine content in tobacco through microbial degradation: research progress and potential applications.

Zi-Jia Li, Dong-Dong Yang, Zhi-Yun Wei, Jie Huang, Yi-Qian Chi, You-Xuan Lu, Feng-Wei Yin

Abstract readReview
In one paragraph

Review in Biotechnology for biofuels and bioproducts, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Microbial community assembly in the fermentation of cigar tobacco leaves.Frontiers in bioengineering and biotechnology · 2026
    Review
  5. Review
  6. Nicotine Degradation byMolecules (Basel, Switzerland) · 2025
    Article
  7. Article
  8. Macrotranscriptomics analysis for decoding the role ofFrontiers in bioengineering and biotechnology · 2025
    Article
  9. Leveraging tobacco for a low-carbon biorefinery.Frontiers in plant science · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zi-Jia LiSchool of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing, 210000, People's Republic of China.
Dong-Dong YangSchool of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing, 210000, People's Republic of China.
Zhi-Yun WeiSchool of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing, 210000, People's Republic of China.
Jie HuangSchool of Life Sciences, Taizhou University, Taizhou, 318000, Zhejiang, People's Republic of China.
Yi-Qian ChiSchool of Life Sciences, Taizhou University, Taizhou, 318000, Zhejiang, People's Republic of China.
You-Xuan LuSchool of Life Sciences, Taizhou University, Taizhou, 318000, Zhejiang, People's Republic of China.
Feng-Wei YinSchool of Life Sciences, Taizhou University, Taizhou, 318000, Zhejiang, People's Republic of China. yinfengwei@126.com.

Funding

Taizhou Scientific and Technological Project No. 22gyb06
6 · The paper itself

Abstract

Originally native to South America, tobacco and is now distributed worldwide as a major cash crop. Nicotine is the main harmful component of tobacco leaves, cigarette smoke and tobacco waste, which severely affects not only the flavor of the tobacco leaf, but also causes great damage to human health. As the anti-smoking movement continued to grow since the 1950s, and consumers become more aware of their health and environmental protection, the world tobacco industry has been committed to research, develop and produce low nicotine cigarette products with relatively low risk to human health. Among various approaches, the use of microorganisms to reduce nicotine content and improve tobacco quality has become one of the most promising methods. Due to increasing interest in nicotine-degrading microorganisms (NDMs), this article reviews recent reports on NDMs, nicotine-degrading enzymes, regulation of nicotine-degrading bacterial consortia and optimization of fermentation conditions, aiming to provide updated references for the in-depth research and application of microorganisms for the degradation of nicotine.

Indexed as

BiotechnologyNicotine-degrading microorganisms (NDMs)Novel tobacco productsTobacco

Identifiers

PMID39695820
PMCPMC11656995

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.