ArticleBMC public health2024
Long-term impact of maternal pre-pregnancy BMI on the risk of overweight/obesity in preschool children: mediation by infant birth weight and BMI trajectory group from 0 to 2 years.
Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- The mediating effects of home environment on the relationship between maternal BMI and childhood obesity: Findings from the ECHO-wide cohort.European journal of pediatrics · 2026Article
- The association of prenatal adiposity characteristics with early childhood overweight and obesity: findings from a large and diverse mother-child cohort.International journal of obesity (2005) · 2026Article
- Late Preschool BMI Acceleration as the Strongest Predictor of Childhood Cardiometabolic Risk at School Entry: A Dual-Trajectory Cohort Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- Association of Maternal Sociodemographic, Anthropometric, and Lifestyle Factors with Childhood Anthropometric Measures and Anxiety Symptoms: A Nationally Representative Cross-Sectional Study of Preschool-Aged Children in Greece.Diseases (Basel, Switzerland) · 2025Article
- The effect of body mass index on maternal and neonatal health in term pregnancies: a cross-sectional study in Turkey.BMC pregnancy and childbirth · 2025Article
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Authors and funding
7 authors.
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Abstract
backgroundObesity is a complex multisystem disease that affects almost every organ system. Studying the early determinants of obesity and implementing targeted interventions have positive implications for promoting long-term health. Therefore, this study was to evaluate the impact of maternal pre-pregnancy overweight or obesity, weight gain rate (WGR) during the second and third trimesters, infant birth weight (IBW) and BMI trajectory group (BMI-TG) from 0 to 2 years on overweight or obesity in preschool children.
methodsA retrospective cohort analysis of data obtained from a hospital was performed using chain-mediated effects to analyze the direct and indirect effects of prepregnancy body mass index (ppBMI)on preschool children's body mass index (pcBMI), and mediated by three variables: WGR, IBW and BMI-TG.
resultsWe found that the effect of ppBMI and pcBMI was significantly mediated by IBW and BMI-TG. After adjusting for confounding factors, the total effect of ppBMI on pcBMI was estimated to be 0.1965 (bootstrap 95% CI: 0.1154-0.2783), the direct effect was 0.1562 (bootstrap 95% CI: 0.0750-0.2362), and the indirect effect was 0.0403 (bootstrap 95% CI: 0.0219 ~ 0.0651). The mediating effect accounted for 20.5% of the variance, indicating that 20.5% of the impact of ppBMI on pcBMI was mediated by two mediating factors: IBW and the BMI-TG.
conclusionsMaternal overweight/obesity before pregnancy had a significant impact on overweight/obesity in preschool children and was mediated by two main factors: IBW and the BMI-TG.
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