Evidence map›Paper›PMID 39695490›Full record

ArticleBMC public health2024

The generic version of China Health Related Outcomes Measures (CHROME-G): psychometric testing and comparative performance with the EQ-5D-5L and SF-6Dv2 among the Chinese general population.

Shitong Xie, Jing Wu, Pinan Chen, Xiaoning He, Kun Zhao, Feng Xie, CHROME Study Group

Abstract readComparative Study
In one paragraph

Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Health utility book: A systematic review and meta-analysis of health utilities in gastric cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shitong XieSchool of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, China.
Jing WuSchool of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, China. jingwu@tju.edu.cn.
Pinan ChenSchool of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, China.
Xiaoning HeSchool of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, China.
Kun ZhaoVanke School of Public Health, Tsinghua University, Beijing, China.
Feng XieDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada.
CHROME Study Group

Funding

National Natural Science Foundation of China 72174142
6 · The paper itself

Abstract

objectivesThe CHROME-G is the first generic preference-based measure developed in China. This study aimed to validate and compare the psychometric properties of the CHROME-G with the EQ-5D-5L and SF-6Dv2 among the Chinese general population.

methodsA representative sample of the Chinese general population in terms of age, gender, education, and urban/rural residence was recruited for an online survey. During the survey, respondents completed three instruments (first the CHROME-G, then the EQ-5D-5L and SF-6Dv2 in random order), demographic and health-related questions. The retest survey was carried out after two weeks. Ceiling/floor effects were first assessed. Convergent and divergent validity was examined using Spearman's rank correlation. Known-group validity was examined using the non-parametric Kruskal-Wallis H test and effect size. Test-retest reliability was assessed using the intraclass correlation coefficient and weighted Kappa statistics.

resultsOne thousand respondents (51.1% male, mean age 44.7 years) completed the first survey, with 378 also completing the retest survey. The mean ± SD completion time was 2.03 ± 0.58 min for the CHROME-G, and 1.37 ± 0.54 and 1.13 ± 0.38 min for the EQ-5D-5L and SF-6Dv2. Only the EQ-5D-5L had a ceiling effect of 35.1%. The range of Spearman rank's correlations was 0.45-0.62 for convergent validity and 0.14-0.46 for divergent validity. Among different health subgroups, the effect size for the CHROME-G, EQ-5D-5L and SF-6Dv2 was 1.348-3.416, 1.362-3.325 and 1.097-2.228, respectively. The ICC for test-retest was 0.791 for the CHROME-G, compared with 0.994 and 0.971 for the EQ-5D-5L and SF-6Dv2.

conclusionsThe CHROME-G showed good and comparable psychometric properties with the EQ-5D-5L and SF-6Dv2.

Indexed as

PsychometricsAdultAgedChinaEast Asian PeopleFemaleHumansMaleMiddle AgedOutcome Assessment, Health CareQuality of LifeReproducibility of ResultsSurveys and QuestionnairesYoung AdultCHROME-GEQ-5D-5LHealth-related quality of lifePsychometric propertySF-6Dv2

Identifiers

PMID39695490
PMCPMC11656610

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.