ArticleNature2025
Hierarchical design of pseudosymmetric protein nanocages.
Abstract read
In one paragraph
Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Solid-state nanopore sensing: the next workhorse of biophysical characterization.Nature methods · 2026Review
- Article
- Article
- Current status on encephalitic alphavirus vaccines development: Advances, challenges, and global health perspectives.Infectious medicine · 2026Review
- Application and Research Progress of Self-Assembling Protein Nanoparticles in Vaccine Development.International journal of molecular sciences · 2026Review
- Review
- Humanized extracellular vesicles for efficient RNA delivery.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Downstream Purification Strategies for Virus-like Particles: A Systematic Review of Structure Preservation, Impurity Control, and Viral Safety.Microorganisms · 2026Review
- Engineering complexity into protein-based biomaterials for biomedical applications.Nature reviews. Materials · 2026Article
- Self-assembled cell-scale containers made from DNA origami membranes.Nature materials · 2026Article
- Self-assembling protein cages: from coiled-coil module to machine learning-drivenMaterials advances · 2026Review
- Precision Labeling of Native Antibodies with Lock Coupling.Journal of the American Chemical Society · 2026Article
- Protein engineering: status report.Protein engineering, design & selection : PEDS · 2026Review
- Transient Occupancy and Pore Dynamics: IP6 Behavior in HIV-1The journal of physical chemistry. B · 2026Article
- Physics Determines and Evolution Shapes Basic Units of Protein Function and Allosteric Regulation.Methods in molecular biology (Clifton, N.J.) · 2026Review
- From Light to Life: Molecular Mechanisms and Macroscopic Transformations in Photoresponsive Hydrogels.Polymer science & technology (Washington, D.C.) · 2025Review
- Humanized Extracellular Vesicles for Efficient RNA Delivery.bioRxiv : the preprint server for biology · 2025Article
- From toroids to helical tubules: Kirigami-inspired programmable assembly of two-periodic curved crystals from DNA origami.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Construction of artificial organellesChemical science · 2025Review
- Protein nanocages: A new frontier in mucosal vaccine delivery and immune activation.Human vaccines & immunotherapeutics · 2025Review
Corrections and comments
- Update of
- Update of
Authors and funding
15 authors.
Quinton M DowlingDepartment of Bioengineering, University of Washington, Seattle, WA, USA.
Young-Jun ParkDepartment of Biochemistry, University of Washington, Seattle, WA, USA.ORCID 0000-0003-2901-6949
Chelsea N FriesInstitute for Protein Design, University of Washington, Seattle, WA, USA.
Neil C GerstenmaierInstitute for Protein Design, University of Washington, Seattle, WA, USA.
Sebastian OlsInstitute for Protein Design, University of Washington, Seattle, WA, USA.ORCID 0000-0001-9784-7176
Erin C YangInstitute for Protein Design, University of Washington, Seattle, WA, USA.ORCID 0000-0002-1305-9066
Adam J WargackiInstitute for Protein Design, University of Washington, Seattle, WA, USA.
Annie DoseyInstitute for Protein Design, University of Washington, Seattle, WA, USA.
Yang HsiaInstitute for Protein Design, University of Washington, Seattle, WA, USA.ORCID 0000-0001-7467-8373
Rashmi RavichandranInstitute for Protein Design, University of Washington, Seattle, WA, USA.
Carl D WalkeyInstitute for Protein Design, University of Washington, Seattle, WA, USA.
Anika L BurrellDepartment of Biochemistry, University of Washington, Seattle, WA, USA.
David VeeslerDepartment of Biochemistry, University of Washington, Seattle, WA, USA.ORCID 0000-0002-6019-8675
David BakerInstitute for Protein Design, University of Washington, Seattle, WA, USA.ORCID 0000-0001-7896-6217
Neil P KingInstitute for Protein Design, University of Washington, Seattle, WA, USA. neilking@uw.edu.ORCID 0000-0002-2978-4692
Funding
CHEETAH Center for the Structural Biology of HIV Infection, Restriction, and Viral DynamicsU54AI170856 · NIAID · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI WALTHER H MOTHES · 2022 to 2026
$34.4MCenters for Research on Structural Biology of Infectious Diseases: Universal Influenza Vaccine Research75N93022C00036 · NIAID · SEATTLE CHILDREN'S HOSPITAL · PI STAKER, BART · 2022 to 2025
$21.7MStructure-based design of broadly protective coronavirus vaccinesP01AI167966 · NIAID · UNIVERSITY OF WASHINGTON · PI Francois J Villinger · 2022 to 2026
$15.3MWaters Select Series Cyclic IMS for P41 Native MS Resource Application to Alzheimer's DiseaseP41GM128577 · NIGMS · OHIO STATE UNIVERSITY · PI GILBERT, JOSHUA DAVID · 2018 to 2022
$7.6MUnraveling the bat humoral immune response against zoonotic viruses to guide the design of next-generation therapeuticsDP1AI158186 · NIAID · UNIVERSITY OF WASHINGTON · PI VEESLER, DAVID · 2020 to 2024
$5.4MGates Foundation INV-010680NIAID NIH HHS 75N93022C00036NIAID NIH HHS DP1 AI158186NIAID NIH HHS P01 AI167966NIAID NIH HHS U54 AI170856NIGMS NIH HHS P41 GM128577
Abstract
Discrete protein assemblies ranging from hundreds of kilodaltons to hundreds of megadaltons in size are a ubiquitous feature of biological systems and perform highly specialized functions
Indexed as
NanostructuresProtein EngineeringProteinsModels, MolecularProtein SubunitsProteinsProtein Subunits
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.