ArticleProstate cancer and prostatic diseases2025
Radical prostatectomy without prostate biopsy based on a noninvasive diagnostic strategy: a prospective single-center study.
Article in Prostate cancer and prostatic diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Identifying Candidates for Biopsy Omission in Prostate Cancer Using mpMRI and PSMA PET/CT.European urology open science · 2026Article
- The value of [Quantitative imaging in medicine and surgery · 2026Article
- Article
- Evolution of the prostate cancer diagnostic paradigm: integrated evidence and clinical pathways from targeted biopsy to biopsy-free strategy.Frontiers in oncology · 2026Review
- Biopsy-free radical prostatectomy: a narrative review considering rationale, limitations, and current data.Prostate international · 2025Review
- Biopsy-free radical prostatectomy for prostate cancer-modern reality or pipe dream?Translational andrology and urology · 2025Article
- A Comparison of Periodic Rebiopsy versus Patient-Based Rebiopsy in Prostate Cancer Active Surveillance.Cancer control : journal of the Moffitt Cancer CenterArticle
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Authors and funding
11 authors.
Funding
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Abstract
backgroundProstate biopsy is the most common approach for diagnosing prostate cancer (PCa); however, it has inherent limitations, such as the invasive procedure, postoperative complications, and false negative results. We aimed to provide a noninvasive diagnostic strategy for patients with highly suspected PCa and to evaluate the feasibility of performing biopsy-spared radical prostatectomy.
methodsThis prospective study included a total of 57 patients between November 10, 2022, and December 1, 2023. All 57 patients underwent radical prostatectomy without prior prostate biopsy based on a noninvasive diagnostic strategy consisting of a diagnostic prediction model [comprised of the prostate imaging-reporting and data system (PI-RADS) score and prostate-specific antigen density (PSAD)] and the
resultsOf the 371 screened patients with clinically suspected PCa, 57 patients fulfilled the criteria and consented to participate in this study. The median PSAD level was 0.56 (0.42-0.82) ng/mL
conclusionsWe proposed a noninvasive diagnostic strategy consisting sequentially of a diagnostic prediction model and the
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