Evidence map›Paper›PMID 39695047›Full record

ReviewWorld journal of pediatrics : WJP2025

Malignant vasovagal syncope in children.

Wen-Rui Xu, Hong-Fang Jin, Jun-Bao Du, Ying Liao

Abstract readReview
PubMed Publisher
In one paragraph

Review in World journal of pediatrics : WJP, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. [How I treat vasovagal syncope in children].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wen-Rui XuDepartment of Pediatrics, Children's Medical Center, Peking University First Hospital, No. 8, Xishiku Street, West District, Beijing, 100034, China.
Hong-Fang JinDepartment of Pediatrics, Children's Medical Center, Peking University First Hospital, No. 8, Xishiku Street, West District, Beijing, 100034, China.
Jun-Bao DuDepartment of Pediatrics, Children's Medical Center, Peking University First Hospital, No. 8, Xishiku Street, West District, Beijing, 100034, China. junbaodu1@126.com.
Ying LiaoDepartment of Pediatrics, Children's Medical Center, Peking University First Hospital, No. 8, Xishiku Street, West District, Beijing, 100034, China. liaoyingwww@163.com.

Funding

Clinical Medicine Plus X - Young Scholars Project PKU2022LCXQ028National High-Level Hospital Clinical Research Funding (Multi-center Clinical Research Project of Peking University First Hospital) 2022CR59
6 · The paper itself

Abstract

backgroundMalignant vasovagal syncope (VVS) is a unique form of cardioinhibitory VVS, characterized by prolonged asystole. To deepen the understanding of this distinct type of VVS in children, this article reviews advancements in the potential pathogenesis, diagnostic approaches, clinical significance, and treatment controversies of malignant VVS in pediatric patients. DATA SOURCES: This article was developed by reviewing the literature and studies in databases including PubMed and Chinese Journal Full-text Database up to September 2024. Search terms included "malignant vasovagal syncope" AND "children" or "vasovagal syncope" AND "asystole" AND "children".

resultsTo date, studies focused on malignant VVS in children remain limited. Theoretically, children with malignant VVS are at risk of physical or mental impairment due to this cardiac asystole, though no definite conclusions have been reached. The mechanism underlying the significant cardiac inhibition in malignant VVS remains unclear, and the treatment strategy of malignant VVS is debatable.

conclusionsThe understanding of children with malignant VVS is insufficient. Further research is required to evaluate the clinical features and the pathogenesis of pediatric VVS with cardiac asystole and to establish effective management strategies for malignant VVS. Video Abstract.

Indexed as

Syncope, VasovagalChildHumansAsystoleDiagnosisPathogenesisPediatricsTreatmentVasovagal syncope

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.