Evidence map›Paper›PMID 39694976›Full record

ArticlePlanta2024

Biased allele transmission for herbicide resistance: a conditional gene drive.

Anthony J Conner, Jeanne M E Jacobs

Abstract read
PubMed Publisher
In one paragraph

Article in Planta, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Anthony J ConnerAgResearch, Christchurch, New Zealand.ORCID http://orcid.org/0000-0003-4857-1761
Jeanne M E JacobsAgResearch, Christchurch, New Zealand. jeanne.jacobs@agresearch.co.nz.ORCID http://orcid.org/0000-0002-1047-1039

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MAIN

conclusionHerbicide application to plants heterozygous for herbicide resistance results in distorted segregation favoring resistant allele transmission resulting in a conditional gene drive. Brassica napus plants heterozygous for an allele conferring sulfonylurea resistance at a single locus exhibit normal Mendelian inheritance. However, following application of the herbicide, highly distorted segregation of herbicide resistance occurs among progeny. Screening progeny from controlled crosses demonstrated that the herbicide imposes in planta gametic selection against pollen and ovules with the recessive allele for herbicide susceptibility, as well as embryonic selection against embryos homozygous for the susceptible allele. Such inducible biased inheritance represents a conditional form of allele transmission following herbicide application and mimics a natural gene drive. We postulate that natural gene drives are common in plant populations and can operate in a conditional manner resulting in non-Mendelian inheritance in response to abiotic and biotic stresses.

Indexed as

AllelesBrassica napusHerbicide ResistanceHerbicidesCrosses, GeneticSulfonylurea CompoundsHerbicidesSulfonylurea CompoundsAcetohydroxyacid synthaseBiased segregationBrassica napusChlorsulfuron resistanceDistorted segregationEmbryonic selectionGametic selectionHerbicide resistanceSulfonylurea resistance

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.