Evidence map›Paper›PMID 39694931›Full record

ArticleVirchows Archiv : an international journal of pathology2025

Interstitial lipoid pneumonia-A complication of intravenous administration of lipid emulsions in critically ill patients.

E M V de Cuba, W Vreuls, C G Tan, D B Flieder, E Thunnissen

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In one paragraph

Article in Virchows Archiv : an international journal of pathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Morphological artifacts in pulmonary pathology and literature review.Virchows Archiv : an international journal of pathology · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

E M V de CubaDepartment of Pathology, VU University Medical Center, Room 0E48, De Boelelaan 1117 1081 HV, Amsterdam, The Netherlands.
W VreulsDepartment of Pathology, Canisius Wilhelmina Ziekenhuis, Nijmegen, The Netherlands.
C G TanDepartment of Pulmonology, VU University Medical Center, Amsterdam, The Netherlands.
D B FliederDepartment of Pathology, Fox Chase Cancer Centre, Philadelphia, PA, USA.
E ThunnissenDepartment of Pathology, VU University Medical Center, Room 0E48, De Boelelaan 1117 1081 HV, Amsterdam, The Netherlands. e.thunnissen@amsterdamumc.nl.ORCID http://orcid.org/0000-0003-0243-4657

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipoid pneumonia is a rare entity most often associated with inhalation of foreign material (i.e. "fire-eater's lung"), silicone injection, and severe trauma. We present the case of a 61-year old man who developed acute respiratory distress syndrome following endoscopic retrograde cholangiopancreatography (ERCP) for cholelithiasis. Intensive care supportive therapy included mechanical ventilation, dialysis, and total parenteral nutrition. Unresolved pneumothorax necessitated lobectomy. Histology of the lobectomy specimen demonstrated massive intra-alveolar haemorrhage and numerous alveolar septal macrophages with clear cytoplasmic vacuoles. These findings were diagnostic of interstitial lipoid pneumonia due to intravenous administration of lipid emulsions. The differential diagnosis is also discussed. Although rare, interstitial lipoid pneumonia should be considered in critically ill patients presenting with an interstitial pattern of lung disease after intravenous administration of lipid emulsions.

Indexed as

Fat Emulsions, IntravenousPneumonia, LipidCholangiopancreatography, Endoscopic RetrogradeCritical IllnessHumansMaleMiddle AgedRespiratory Distress SyndromeFat Emulsions, IntravenousARDSBleeding complicationIntralipidLipoid pneumoniaPathology

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.