Evidence map›Paper›PMID 39694861›Full record

ReviewPrenatal diagnosis2025

Indications and Outcomes of Fetal Cystoscopy for Lower Urinary Tract Obstruction: A Comprehensive Review.

Ugo Maria Pierucci, Irene Paraboschi, Giulia Lanfranchi, Matthieu Peycelon, Gloria Pelizzo, Rodrigo Ruano

Abstract readReview
In one paragraph

Review in Prenatal diagnosis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ugo Maria PierucciDepartment of Pediatric Surgery, Ospedale Dei Bambini Vittore Buzzi, Milan, Italy.ORCID 0000-0001-7370-5122
Irene ParaboschiDepartment of Biomedical and Clinical Sciences, University of Milano, Milan, Italy.ORCID 0000-0003-3529-1437
Giulia LanfranchiDepartment of Pediatric Surgery, Ospedale Dei Bambini Vittore Buzzi, Milan, Italy.
Matthieu PeycelonDepartment of Pediatric Surgery and Urology, National Reference Center for Rare Urinary Tract Malformations (CRMR MARVU), ERN eUROGEN Accredited Center, Hopital Universitaire Mere-enfant Robert-Debre, APHP, GHU North, Université Paris Cité, Paris, France.ORCID 0000-0003-3617-4849
Gloria PelizzoDepartment of Pediatric Surgery, Ospedale Dei Bambini Vittore Buzzi, Milan, Italy.
Rodrigo RuanoDivision of Maternal-Fetal Medicine, Department of Maternal and Fetal Medicine, Obstetrics and Gynecology, Miller School of Medicine, University of Miami, Miami, Florida, USA.ORCID 0000-0002-3642-5858

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fetal lower urinary tract obstruction (LUTO) encompasses a spectrum of rare congenital anomalies affecting the fetal urinary system, leading to significant morbidity and mortality. This condition, arising from various anatomical anomalies such as posterior urethral valves (PUV), urethral atresia, and cloacal malformations, disrupts normal urine flow, resulting in secondary complications such as pulmonary hypoplasia and renal impairment. Current management strategies, including fetal vesicoamniotic shunting (VAS) and fetal cystoscopy, aim to alleviate obstruction and mitigate associated risks. While VAS has been a longstanding intervention, fetal cystoscopy presents a promising alternative by enabling direct visualization and targeted treatment of urinary tract obstructions. However, fetal cystoscopy is not without challenges, including technical complexities and risks associated with invasive procedures. This review explores the rationale, indications, technical considerations, outcomes, and future innovations of fetal cystoscopy in managing LUTO. It highlights the critical role of accurate diagnosis, patient selection, and procedural expertise in optimizing fetal and maternal outcomes. Despite existing challenges, ongoing advancements in technology and clinical practice hold the potential for further enhancing the safety and efficacy of fetal cystoscopy, underscoring its evolving role in prenatal care.

Indexed as

CystoscopyFetal DiseasesUrethral ObstructionFemaleHumansPregnancybladder outlet obstructioncongenital anomalies of the kidney and urinary tractfetal cystoscopyfetal surgeryfetal therapyfetal vesicoamniotic shuntlower urinary tract obstructionmegacystisprenatal diagnosisultrasound

Identifiers

PMID39694861
PMCPMC11717740

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.