Evidence map›Paper›PMID 39694806›Full record

SynthesisJournal of neurointerventional surgery2025

What can we learn from machine learning studies on flow diverter aneurysm embolization? A systematic review.

Esref Alperen Bayraktar, Jonathan Cortese, Mohamed Sobhi Jabal, Sherief Ghozy, Atakan Orscelik, Cem Bilgin, Ramanathan Kadirvel, Waleed Brinjikji, David F Kallmes

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of neurointerventional surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Esref Alperen BayraktarDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA bayraktar.esref@mayo.edu.ORCID http://orcid.org/0000-0002-8245-2689
Jonathan CorteseDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.ORCID http://orcid.org/0000-0002-1616-9113
Mohamed Sobhi JabalDepartment of Radiology, Duke University Health System, Durham, North Carolina, USA.
Sherief GhozyDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.ORCID http://orcid.org/0000-0001-5629-3023
Atakan OrscelikDepartment of Neurosurgery, University of California San Francisco, San Francisco, California, USA.ORCID http://orcid.org/0000-0001-6481-3076
Cem BilginDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.ORCID http://orcid.org/0000-0003-1832-1278
Ramanathan KadirvelDepartment of Neurosurgery, Mayo Clinic, Rochester, Minnesota, USA.ORCID http://orcid.org/0000-0002-6786-9953
Waleed BrinjikjiDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.ORCID http://orcid.org/0000-0001-5271-5524
David F KallmesDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.

Funding

Computational and Biological Approach to Flow DiversionR01NS076491 · NINDS · MAYO CLINIC ROCHESTER · PI Juan R Cebral, DAVID F KALLMES · 2011 to 2026
$7.4M
Drug Eluting Embolization Coils for Improved Treatment of Intracranial AneurysmsR44NS107111 · NINDS · ANCURE, LLC · PI BETTINGER, CHRISTOPHER JOHN, KADIRVEL, RAMANATHAN · 2018 to 2020
$1.2M
Enhanced endothelialization of nanomatrix coated flow diverter for intracranial aneurysmsR43NS110114 · NINDS · ENDOMIMETICS, LLC · PI HWANG, PATRICK, KADIRVEL, RAMANATHAN · 2019 to 2019
$563k
Rapidly healing flow diverters using magnetic cell targeting for intracranial aneurysm treatmentR21NS128199 · NINDS · MEDICAL COLLEGE OF WISCONSIN · PI KADIRVEL, RAMANATHAN, TEFFT, BRANDON J · 2022 to 2023
$447k
NINDS NIH HHS R01 NS076491NINDS NIH HHS R21 NS128199NINDS NIH HHS R43 NS110114NINDS NIH HHS R44 NS107111
6 · The paper itself

Abstract

backgroundAs the use of flow diverters has expanded in recent years, predicting successful outcomes has become more challenging for certain aneurysms.

objectiveTo provide neurointerventionalists with an understanding of the available machine learning algorithms for predicting the success of flow diverters in occluding aneurysms.

methodsThis study followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, and the four major medical databases (PubMed, Embase, Scopus, Web of Science) were screened. The study included original research articles that evaluated the predictive abilities of various machine learning algorithms for determining the success of flow diverters in achieving aneurysm occlusion.

resultsFive studies out of 217 were included based on our criteria. The included studies used various variables (patient demographics, aneurysm and parent artery characteristics, flow diverter and hemodynamic-related features, and angiographic parametric imaging) to predict flow diverter treatment outcomes. The machine learning algorithms used, along with their respective accuracy rates, were as follows: logistic regression (61% and 85%), support vector machine (88%), Gaussian support vector machine (90%), linear support vector machine (85%), decision tree (80%), random forest (87%), k-nearest neighbors (83% and 85%), XGBoost (87%), CatBoost (86%), deep neural networks (77.9%), and recurrent neural networks (74%).Two studies trained the machine learning models with both all features and the most significant features. Both studies observed that the accuracy of machine learning models decreased by removing the insignificant features.

conclusionThe current literature indicates that machine learning algorithms can be trained to predict the success of flow diverters with an accuracy of up to 90%.

Indexed as

Embolization, TherapeuticIntracranial AneurysmMachine LearningHumansAneurysmFlow Diverter

Identifiers

PMID39694806
PMCPMC12301989

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.